Clinical trials · Pennsylvania
Ulcer clinical trials in Pennsylvania
We’re tracking 46 recruiting ulcer studies with a site in Pennsylvania — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06283979RecruitingPhase 2
Antibiotic bone filler vs standard care for infected pressure ulcers
This trial tests a special antibiotic bone filler (STIMULAN VG) compared to standard care for people with a serious pressure ulcer that has infected the bone. You need to be able to have surgery to clean and close the wound.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06104969Recruiting
Biomarkers for active diabetic foot ulcers
This study is looking for people with diabetes who have an open foot or ankle ulcer. Researchers want to collect samples to find biomarkers, which are natural signs in the body that could help improve treatment and healing. It may be a good fit if you have a diabetic foot ulcer and are not currently in another drug trial for ulcers.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06095128RecruitingPhase 4
Combination therapy for ulcerative colitis
This study tests two drugs together, vedolizumab and tofacitinib, to see if they are more effective than either alone in treating moderate to severe ulcerative colitis. It may be an option if other treatments have not worked well for you.
Wexford, PennsylvaniaAges 18–65 - NCT06100289RecruitingPhase 3
Study of vedolizumab for kids with ulcerative colitis or Crohn's disease
This trial tests vedolizumab, a biologic medicine that reduces inflammation, in children and teenagers who have moderate to severe ulcerative colitis or Crohn's disease and have not responded well to other treatments.
Hershey, PennsylvaniaAges 2–17 - NCT05987852Recruiting
Hyperbaric oxygen therapy for ulcerative colitis flare
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) can help people hospitalized with a moderate to severe ulcerative colitis flare get better faster. You will receive the therapy along with standard steroid treatment.
Pittsburgh, PennsylvaniaAges 18–85 - NCT05758545Recruiting
Device treatment for diabetic foot ulcers with poor blood flow
This trial tests whether COMS One is safe and effective for healing a specific diabetic foot ulcer. It may help people whose ulcer is not healing well, especially when blood flow to the foot is limited.
McKeesport, PennsylvaniaAges 22–90 - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Pittsburgh, PennsylvaniaAges 2 years+ - NCT05076175RecruitingPhase 2/Phase 3
Oral ozanimod for children with moderate to severe ulcerative colitis
This trial tests whether an oral medicine called ozanimod can improve ulcerative colitis (UC) in children whose disease is moderate to severe. It’s meant for kids who didn’t fully respond—or couldn’t tolerate—standard UC treatments.
Hershey, PennsylvaniaAges 2–17 - NCT07223424RecruitingPhase 2
Patient preference study: shot vs infusion for immunotherapy
This study compares two ways to take immunotherapy drugs (nivolumab or pembrolizumab): as a shot under the skin (subcutaneous) versus an infusion into a vein (intravenous). It looks at which method patients prefer and is for people with certain advanced cancers where these drugs are already approved.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07198113Recruiting
Comparing newer treatments for pediatric inflammatory bowel disease
This study is for children and teens with inflammatory bowel disease (Crohn's, colitis, or indeterminate) whose previous anti-TNF medicine stopped working. It compares several newer treatments to see which works best.
Pittsburgh, PennsylvaniaAges 1–18 - NCT06742801Recruiting
Onyx liquid embolic for active bleeding outside the brain and heart
This trial tests a liquid material called Onyx that is injected into blood vessels to stop active bleeding in areas like the arms, legs, belly, or chest. It may help people with uncontrolled bleeding that needs to be blocked quickly.
Pittsburgh, PennsylvaniaAges 22 years+ - NCT06571669Recruiting
Nerve stimulation device for ulcerative colitis
This trial tests a new medical device called BOOM-IBD2 that uses gentle nerve stimulation to treat ulcerative colitis. It's for people who have not had UC surgery and do not have certain infections or other implanted devices.
Philadelphia, PennsylvaniaAges 18–85 - NCT06560021Enrolling by invitation
Random biopsies in inflammatory bowel disease surveillance
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06424769Enrolling by invitation
Managing Inflammatory Bowel Disease with Text Message Surveys
This study aims to improve care and reduce health gaps for people with inflammatory bowel disease using text-message surveys to track symptoms and guide better disease management.
Philadelphia, PennsylvaniaAges 13 years+ - NCT06213649RecruitingPhase 3
Ulcer treatment trial for active eye infection
This trial tests a new treatment for people who still have eye inflammation after 1 month of standard treatment for a parasitic eye infection (acanthamoeba keratitis). It aims to find a better way to control the infection and reduce inflammation.
Philadelphia, PennsylvaniaAges 8 years+ - NCT04471909Recruiting
Stent graft for aortic arch problems in high-risk patients
This study tests a new stent graft device to treat problems in the aortic arch, such as aneurysms or chronic dissections, without open surgery. It may help people who are not good candidates for traditional open repair.
Wynnewood, PennsylvaniaAges 18 years+ - NCT05705024RecruitingPhase 2
Eye drops/treatment to heal stubborn cornea surface damage
This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05172089Recruiting
Treating recurring infection in diabetic foot ulcers
This trial studies an approach to treat bacteria living in a diabetic foot ulcer and help prevent the ulcer from coming back. You may be able to join if you have an open diabetic foot ulcer and good blood flow to the wound.
Cranberry Township, PennsylvaniaAges 18 years+ - NCT04243525Recruiting
Inflammatory bowel disease patient research registry
This study is a research registry that collects information from adults receiving care for inflammatory bowel disease at UPMC. It may help researchers better understand bowel disease and improve future treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune disease
This trial tests whether the immunotherapy drug nivolumab can safely treat advanced cancer in people who also have an autoimmune disease like rheumatoid arthritis, lupus, or multiple sclerosis. It aims to find out if the drug may help control cancer while managing their autoimmune condition.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02791854Enrolling by invitation
Improving Care for Adults With Crohn’s or Ulcerative Colitis
This trial looks at ways to improve care for adults living with inflammatory bowel disease, including Crohn’s disease and ulcerative colitis. You may be invited if your clinic is part of an inflammatory bowel disease care network called IBD Qorus.
Hershey, PennsylvaniaAges 18–99 - NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21
Ulcer trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting ulcer studies listed above.
- University of Pennsylvania · 4 studies
- University of Pittsburgh Medical Center · 4 studies
- Allegheny Health Network · 2 studies
- University of Pittsburgh · 2 studies
- UPMC Hillman Cancer Center · 2 studies
- Allegheny General Hospital
- Children's Hospital of Philadelphia
- Lankenau Medical Center
What taking part in a ulcer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Ulcer trials in other states
Common questions
- Are there ulcer clinical trials in Pennsylvania?
- Yes. We're currently tracking 46 recruiting ulcer studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a ulcer study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a ulcer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New ulcer studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.