Clinical trials
Upper Extremity clinical trials
Below are recruiting upper extremity clinical trials, each written for real people, not researchers. We’re tracking 138 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05301140Recruiting
Registry study for paired VNS after stroke
This study follows people who already have the Vivistim device implanted after an ischemic stroke affecting arm or hand function. It may help researchers better understand how paired nerve stimulation therapy works in real-world care.
Orlando, FloridaAges 22 years+ - NCT05191121Enrolling by invitation
Rehab program to improve arm and trunk control after spinal injury
This trial helps people with recent traumatic spinal cord injury improve arm movement and trunk (upper body) stability using a training program that includes electrical stimulation. If you’re early after injury and can safely use stimulation, you may benefit from more controlled movement for daily tasks.
Englewood, ColoradoAges 18 years+ - NCT04534556Enrolling by invitation
Wireless nerve stimulation to improve stroke recovery
This study tests a wireless nerve stimulation device placed near the vagus nerve to help people recover after a stroke. It focuses on people with specific remaining arm/hand movement and recovery levels at least 12 months after stroke.
Dallas, TexasAges 22–79 - NCT04430218Recruiting
Peripheral interfaces for better prosthetic arm control
This trial tests a surgically placed device that connects to arm nerves to improve control and feeling in a prosthetic arm. It may help people with upper limb amputations who already use or are prescribed a myoelectric prosthesis.
Cleveland, OhioAges 21 years+ - NCT03882073Recruiting
Upper arm amputation rehab study to improve hand control and feel
This trial tests a new approach for rehabilitation after an upper-limb amputation to help improve your ability to intentionally control a prosthetic and regain a sense of position (“proprioception”). You may be considered if you are planning an elective upper-arm or below-elbow amputation and can safely have surgery and follow up closely.
Bethesda, MarylandAges 18–65 - NCT03400345Recruiting
Follow-up for transplanted arm patients
This study follows people who received a transplanted arm (or both arms) to learn from their ongoing care. You may be asked for small tissue samples (biopsies) and to continue an immunotherapy plan to help protect the transplant.
Baltimore, MarylandAges 18–100 - NCT01459107RecruitingPhase 2
Upper arm transplant study using immune treatment
This trial tests replacing a missing or non-working lower arm/hand with a donated upper limb (transplant). It also uses a special immune treatment plan and bone marrow infusion to help the body accept the new limb, aiming to improve hand function and quality of life.
Baltimore, MarylandAges 18–69 - NCT05809622Recruiting
Arm and elbow exercises for a sore tennis elbow
This study compares two exercise programs to see which helps people with long-lasting pain on one elbow (tennis elbow). If you have symptoms for at least 3 months, the trial may help improve pain and function using supervised, elbow-focused training.
IstanbulAges 18–65 - NCT06156904Recruiting
Study of b.Bone bone graft for defects in arms, legs, pelvis
This trial is following patients who receive a bone graft using a product called b.Bone to treat bone defects in the arms, legs, or pelvis. Researchers will collect information during your regular follow-up visits to see how well the bone heals.
BerlinAges 18 years+ - NCT07834333Recruiting
Brain stimulation to help arm and leg recovery after stroke
This trial tests a non-invasive brain stimulation technique called theta burst stimulation to see if it can improve arm and leg function in people who recently had a stroke. It may help with movement recovery in the first few months after stroke.
Ankara, YenimahalleAges 45 years+ - NCT07685730Recruiting
Comparing blood pressure readings in arm vs leg during C-section
This study compares blood pressure measurements taken from the arm versus the leg during planned Cesarean sections using a special monitor. It aims to see which location gives more accurate readings for women having spinal anesthesia.
Columbus, OhioAges 18 years+ - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT06098157Recruiting
Non-healed broken bones in arm or leg after surgery
This is a registry study that collects information from people who have had surgery for a broken arm or leg bone that did not heal on its own. It helps doctors better understand why some bones don't heal and how to improve treatment.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07012642RecruitingEarly Phase 1
GLP-1 drugs for arm or leg swelling (lymphedema)
This trial tests if a class of diabetes drugs (GLP-1 receptor agonists) can reduce swelling in one arm or leg caused by lymphedema. It may help people who have not found relief from other treatments.
Red Bank, New JerseyAges 18 years+ - NCT03135847Enrolling by invitation
Using feedback to improve prosthetic movement in amputees
This study tests whether movement “feedback” can help adults with arm or leg amputations control a prosthetic better. It may be most helpful if you can comfortably wear a prosthetic socket and can understand and consent to the study.
Ages 18–75 - NCT06908538Recruiting
Cryo nerve block for pain after amputation
This study is testing a treatment called a cryo nerve block to reduce pain after amputation, including phantom limb pain. It will look at whether freezing the nerve during surgery helps people feel less pain and use less pain medicine.
Pittsfield, MassachusettsAges 18 years+ - NCT07677969Recruiting
Arm loss, balance, pain, and daily life study
This study looks at how the percentage of arm loss affects balance, neck and back pain, daily activities, and reaction time in people with one arm amputated who use a myoelectric or bionic hand. It may help understand how to improve care and rehabilitation.
AnkaraAges 18–65
Hear when a new Upper Extremity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for upper extremity?
- Yes. Clin2 currently lists 138 recruiting upper extremity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a upper extremity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a upper extremity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.