Freezing nerves to ease pain from muscle tightness
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Immune system & allergy, Injuries & trauma, Pain clinical trials.
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a brain or spinal cord condition like stroke, multiple sclerosis, or spinal cord injury that causes muscle tightness and pain.
- You are 18 or older.
- You have already tried Botox or nerve blocks for this pain and it helped.
- You have a goal to reduce the pain from muscle tightness (like moving easier or sleeping better).
- You have not had Botox or a nerve freezing treatment in the last 3 months.
- You do not have conditions like Raynaud's, cold allergies, bleeding problems, or infection where the treatment would go.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if freezing certain nerves in the upper arm (cryoneurolysis) works as well as standard care for reducing shoulder pain and muscle tightness after a stroke or brain injury. It aims to improve function and ease caregiving tasks.
This study looks at whether a temporary numbing injection (nerve block) can predict how well a longer-lasting freezing treatment (cryoneurolysis) will relieve chronic pain or muscle tightness. If you're eligible, you'll get the freezing treatment, which may provide longer-term relief.
This study tests if freezing a nerve (cryoneurolysis) can reduce muscle tightness (spasticity) and improve arm movement. It also looks at how the brain may change after treatment. If you have tight muscles that improved with a numbing nerve block, you may be eligible.
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
This study tests a cold treatment called cryoneurolysis to reduce painful muscle tightness in the shoulder or elbow for people with cerebral palsy. It is for those who have tried other treatments like injections or medications and found they didn't work well or weren't an option.
This early study tests a procedure that uses extreme cold to freeze specific nerves that may be causing your pain, with the help of a special scan to guide the treatment. It aims to see if this approach can safely reduce chronic pain.
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