Freezing nerves to ease pain from muscle tightness
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Immune system & allergy, Injuries & trauma, Pain clinical trials.
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a brain or spinal cord condition like stroke, multiple sclerosis, or spinal cord injury that causes muscle tightness and pain.
- You are 18 or older.
- You have already tried Botox or nerve blocks for this pain and it helped.
- You have a goal to reduce the pain from muscle tightness (like moving easier or sleeping better).
- You have not had Botox or a nerve freezing treatment in the last 3 months.
- You do not have conditions like Raynaud's, cold allergies, bleeding problems, or infection where the treatment would go.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if freezing certain nerves in the upper arm (cryoneurolysis) works as well as standard care for reducing shoulder pain and muscle tightness after a stroke or brain injury. It aims to improve function and ease caregiving tasks.
This study tests whether a numbing nerve block (injection) can predict if a procedure called cryoneurolysis (freezing a nerve to relieve pain) will work for people with chronic muscle or joint pain or spasticity. It may help you if you have long-lasting pain or muscle tightness.
This study tests if freezing a nerve (cryoneurolysis) can reduce muscle tightness (spasticity) and improve arm movement. It also looks at how the brain may change after treatment. If you have tight muscles that improved with a numbing nerve block, you may be eligible.
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