Clinical trials
Vaccination clinical trials
Below are recruiting vaccination clinical trials, each written for real people, not researchers. We’re tracking 600 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05807035RecruitingPhase 1
Personalized vaccine made from your tumor tissue
This Phase 1 trial tests a personalized (autologous) vaccine made from your own tumor tissue. It’s designed for people with advanced cancers who have already had at least one treatment and may still have options for getting tumor tissue for the vaccine.
Adelaide, South AustraliaAges Any age - NCT05841550RecruitingPhase 1/Phase 2
Vaccine study for high-risk smoldering or myeloma
This Phase 1/2 trial tests a cancer vaccine (TG01/QS-21) in people with high-risk smoldering multiple myeloma or multiple myeloma. It aims to see how safe the vaccine is and whether it can help the immune system control the disease.
Oslo, OsloAges 18 years+ - NCT05886439RecruitingPhase 1/Phase 2
Study drug plus PD-1 or PD-L1 for lung cancer
This Phase 1/2 trial tests a new treatment called LK101 combined with a PD-1 or PD-L1 antibody for advanced lung cancer. It may help shrink tumors and improve control of the disease, especially after prior anti–PD-1/PD-L1 treatment has stopped working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05923333Recruiting
Breastfed infants of HIV-exposed mothers get a probiotic
This study gives a specific probiotic (from B. infantis) to babies born without HIV to see if it can improve the baby’s early immune health. It focuses on babies who are HIV-exposed because their mother has HIV and plans to exclusively breastfeed for the first 6 months.
Cape TownAges birth–50 years - NCT05938192Recruiting
Treatments for HPV-related genital tract changes
This trial studies treatment approaches for conditions caused by human papillomavirus (HPV) in the female genital tract. It may help people whose HPV-related disease is being evaluated for new or combined treatment options.
Milan, LombardyAges 18 years+ - NCT05947890RecruitingPhase 2
Testing an immune-boosting TB vaccine in people with or without HIV
This Phase 2 study tests MTBVAC, a TB vaccine candidate, to see if it is safe and whether it helps the immune system. It may be a fit if you’re eligible for TB and HIV-related vaccine safety testing and can follow study visits and testing.
Johannesburg, GautengAges 12–55 - NCT05952934RecruitingPhase 2
Vaccine trial to help prevent head and neck cancer return
This Phase 2 study tests a Candida-based vaccine to help stop head and neck squamous cell cancer from coming back after curative treatment. If you are currently cancer-free on scans and exams, the trial may help train your immune system to lower recurrence risk.
Fayetteville, ArkansasAges 18–100 - NCT05973084Recruiting
COVID spread study in Malawi households and vaccine recipients
This study tracks how COVID-19 spreads and causes illness in real households in Blantyre, Malawi, and compares groups after infection or vaccination. If you qualify, you’ll do follow-up testing and visits for several months.
Boston, MassachusettsAges 5–75 - NCT06019702RecruitingPhase 1
Personalized mRNA vaccine for advanced digestive cancers
This trial tests a personalized mRNA vaccine designed to target unique markers on your cancer cells. The vaccine is made just for you based on genetic testing of your tumor. It is for people with advanced digestive system cancers who have run out of standard options.
Hangzhou, ZhejiangAges 18–75 - NCT06025487RecruitingPhase 2
Meningococcal B vaccine study for asplenia
This study tests a meningococcal B vaccine in adults who have had their spleen removed or have a spleen that doesn't work well (asplenia). It will compare how well the vaccine works in these patients versus healthy adults to see if it provides good protection.
Vienna, State of ViennaAges 18–60 - NCT06026774RecruitingPhase 1
Personalized mRNA Vaccine After Digestive Cancer Surgery
This trial tests a personalized mRNA vaccine designed to train your immune system to fight your specific cancer. It's for people who have just had surgery to remove a digestive system cancer (like pancreatic or colorectal) and will also receive standard chemotherapy after surgery.
Hangzhou, ZhejiangAges 18–75 - NCT06026800RecruitingPhase 1
Personalized mRNA vaccine plus standard treatment for advanced digestive cancers
This trial tests a personalized mRNA vaccine (iNeo-Vac-R01) given alongside standard first-line treatment for advanced digestive system cancers. The vaccine is made specifically for your tumor's unique genetic changes (neoantigens) and aims to help your immune system fight the cancer more effectively.
Hangzhou, ZhejiangAges 18–75 - NCT06129253Recruiting
GLOBE-HPV: Study of HPV in communities
This study is trying to find out how many people in different communities have HPV (human papillomavirus). It involves collecting samples and answering questions to help estimate the global burden of HPV.
DhakaAges 9–50 - NCT06216470RecruitingPhase 2
Testing an antibody treatment for chronic hepatitis B
This study tests a new antibody treatment (VIR-3434) for chronic hepatitis B. It aims to see if the antibody can help your immune system control the virus, potentially allowing you to stop your current antiviral medication later.
Toronto, OntarioAges 18–65 - NCT06220747Recruiting
HPV vaccine study for women ages 12 to 45
This study tests how well the HPV vaccine works in women and teens. It's for those who are willing to get an HPV test and haven't already had all 3 doses of the vaccine.
Bangkok, Select...Ages 12–45 - NCT06272812RecruitingPhase 2
TB vaccine study for teens and adults
This trial tests whether a new vaccine called MTBVAC can prevent tuberculosis (TB) in people living in areas where TB is common. If you are between 14 and 45 years old and in good health, you may be able to join.
KisumuAges 14–45 - NCT06305910RecruitingPhase 1
Vaccine immunotherapy for recurrent brain tumors or newly diagnosed DIPG
This trial tests a combination of a vaccine made from tumor cells and a drug that may boost the immune system's ability to fight brain tumors. It is for children and young adults with a recurrent high-grade glioma or a newly diagnosed diffuse midline glioma with a specific genetic marker (H3K27M).
Minneapolis, MinnesotaAges 2–25 - NCT07694986RecruitingPhase 2
Vaccine therapy for breast cancer that has spread to the brain and spinal cord
This trial tests a new type of vaccine (dendritic cells) injected directly into the spinal fluid, combined with either trastuzumab (if your breast cancer is HER2-positive) or nivolumab (if your breast cancer is HER2-negative). The goal is to see if this combination can better control breast cancer that has spread to the lining of the brain and spinal cord.
Tampa, FloridaAges 18 years+ - NCT06326736RecruitingEarly Phase 1
mRNA vaccine after surgery for pancreatic cancer
This trial tests a personalized mRNA vaccine (made from your tumor's unique markers) combined with standard chemotherapy after surgery for pancreatic cancer. The goal is to see if the vaccine can help prevent the cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT06380114Recruiting
Standing orders for HPV vaccine
This trial tests if having a 'standing order' (an automatic request) for the HPV vaccine helps more preteens get it. It's for clinics that don't already give HPV shots to most of their teenage patients and have enough 11- and 12-year-olds who still need the vaccine.
Rochester, New YorkAges 9–17 - NCT06381739RecruitingPhase 2
New inhaled COVID-19 booster vaccine trial
This trial tests a next-generation COVID-19 vaccine given as an inhaled mist. It is for adults who have already had at least 3 doses of an mRNA COVID vaccine and are looking for a potentially stronger or longer-lasting immune response.
Halifax, Nova ScotiaAges 18–65 - NCT06389591RecruitingPhase 1
RNA Vaccine for Recurrent Glioblastoma
This trial tests a new personalized RNA vaccine made from your own tumor tissue. It is designed to help your immune system fight the cancer after it has returned. You will have surgery to collect the tumor, and then the vaccine is given to try to stop the tumor from growing again.
Gainesville, FloridaAges 18–80 - NCT06414733RecruitingPhase 1
HER-2 B Cell Peptide Vaccine for Advanced Cancers
This trial tests a vaccine that helps your immune system attack cancer cells that have HER2 or EGFR proteins. It is for people with advanced breast or gastrointestinal cancer whose disease has worsened after standard treatment.
Indianpolis, IndianaAges 18 years+ - NCT06441110RecruitingPhase 3
BCG instillation for medium- to high-risk bladder cancer
This trial tests whether a specific schedule of BCG (a weakened germ that boosts the immune system) placed directly into the bladder is safe and effective for medium- to high-risk bladder cancer that hasn't grown into the muscle. It aims to see if adjusting the standard BCG course can work better for people with a PD-L1-positive tumor.
Fuzhou, FujianAges 18–75
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Common questions
- Are there clinical trials for vaccination?
- Yes. Clin2 currently lists 600 recruiting vaccination studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccination trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccination trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.