Clinical trials
Vaccination clinical trials
Below are recruiting vaccination clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06810934RecruitingPhase 1/Phase 2
New COVID-19 vaccine study for those with prior mRNA vaccines
This study tests a new type of COVID-19 vaccine that is designed to train your immune system to make stronger, longer-lasting protection. You may be able to join if you are 40–64, have already had at least two doses of a mRNA COVID-19 vaccine (Pfizer or Moderna) more than 4 months ago, and are generally healthy.
Los Angeles, CaliforniaAges 40–64 - NCT06808776Recruiting
Stories to prevent HPV cancers
This trial tests if sharing stories can help parents decide to get their child the HPV vaccine. It is for parents of children ages 9 to 12 who have not yet started the HPV shot series.
Hershey, PennsylvaniaAges 18 years+ - NCT06799494RecruitingPhase 4
Testing a reduced dose of the HPV vaccine
This study tests whether a single dose of the HPV vaccine is enough to protect against the viruses that cause several cancers. You will have the vaccine and some small tissue samples taken to see how your immune system responds.
Decatur, GeorgiaAges 18–45 - NCT06784167Recruiting
Vaccine response after CAR-T for myeloma and lymphoma
This study looks at how well vaccines work in people with multiple myeloma or certain lymphomas after they receive CAR-T cell therapy. It aims to help doctors understand the best way to revaccinate patients to protect against preventable diseases.
Portland, OregonAges 18 years+ - NCT06760208Recruiting
Learning about Prevenar 20 in the real world in Korea
This study is for people who are already getting the Prevenar 20 vaccine (a shot that protects against pneumonia and other infections) as part of their regular care. The researchers want to see how well it works in the real world, so it's a simple way to help improve vaccines for everyone.
SeoulAges 1 month+ - NCT05841550RecruitingPhase 1/Phase 2
Vaccine study for high-risk smoldering or myeloma
This Phase 1/2 trial tests a cancer vaccine (TG01/QS-21) in people with high-risk smoldering multiple myeloma or multiple myeloma. It aims to see how safe the vaccine is and whether it can help the immune system control the disease.
Oslo, OsloAges 18 years+ - NCT06665035RecruitingPhase 3
Dengue vaccine study for infants and toddlers
This trial tests two doses of a dengue vaccine in healthy infants and toddlers aged 6 to 21 months. It aims to see if the vaccine is safe and helps protect against dengue fever.
Barranquilla, AtlánticoAges 6 months–1.7 years - NCT03323112Recruiting
Studying immune responses to seasonal flu shots in health workers
This study looks at how your immune system (your body’s infection-fighting system) responds after you get the seasonal flu vaccine. It may help researchers understand what the vaccine triggers in people working in healthcare and labs.
HelsinkiAges 18–64 - NCT06620185Recruiting
Flu immunity study: Vaccination and infection in lungs
This study looks at how your lungs and lymph nodes respond to flu infection and the nasal flu vaccine. It will help researchers understand how to create better protection against the flu.
LondonAges 18–55 - NCT06630884RecruitingPhase 1
Immune response to trauma and fear
This study looks at how the body's immune and stress systems work together in people who have experienced trauma, by giving a harmless vaccine to temporarily boost inflammation. It may help explain why some people develop PTSD and others don't, which could lead to better treatments.
San Francisco, CaliforniaAges 18–65 - NCT06622434RecruitingPhase 1/Phase 2
Vaccine for glioblastoma after standard treatment
This trial tests an experimental vaccine for glioblastoma, given after the usual radiation and chemotherapy (temozolomide). The goal is to see if the vaccine helps the immune system fight remaining cancer cells.
Paris, IdfAges 18–75 - NCT06617715RecruitingPhase 3
Pneumonia vaccine trial for infants and children
This trial tests a 13-valent pneumococcal conjugate vaccine to prevent pneumonia and serious infections caused by pneumococcus bacteria. It may be a good option if your child has never had a pneumococcal vaccine before.
Zhengzhou, HenanAges 1 month–5 years - NCT06612515Recruiting
Vaccine response in patients with weak immune systems
This study looks at how well vaccines for respiratory viruses work in people with weakened immune systems. It may help doctors give better vaccine advice to patients like you.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT06585241RecruitingPhase 4
Study of Updated COVID-19 Vaccines for High-Risk Groups
This trial tests updated COVID-19 vaccines designed to better protect against current variants. It's for people who have already been vaccinated and are at higher risk for severe COVID-19.
Atlanta, GeorgiaAges 6 months+ - NCT06596148Enrolling by invitation
Improving shingles vaccination for veterans on immune-suppressing drugs
This trial tests a way to help doctors encourage more veterans to get the Shingrix vaccine, which protects against shingles. It focuses on veterans taking medications that weaken the immune system.
San Francisco, CaliforniaAges Any age - NCT06564623RecruitingPhase 1
Peptide vaccine plus immunotherapy for biliary tract cancer
This trial tests a personalized peptide vaccine combined with two immunotherapy drugs (durvalumab and tremelimumab) for patients with biliary tract cancer whose tumors have specific genetic changes. The goal is to see if this combination can shrink tumors or slow their growth.
Baltimore, MarylandAges 18 years+ - NCT06535139Recruiting
HPV Vaccine Study for Rural Kids 8 to 12
This study aims to help prevent HPV-related cancers by increasing HPV vaccination rates in rural areas. It is for parents of 8- to 12-year-olds who have not yet completed the two-dose HPV vaccine series.
Gainesville, FloridaAges 8–99 - NCT06513286RecruitingPhase 1/Phase 2
Therapeutic hepatitis B vaccine study using a two-part shot
This trial tests a new vaccine to treat chronic hepatitis B. It's for people who have been on antiviral medication for at least 6 months and still have a low level of the virus in their blood.
FrankfurtAges 18–70 - NCT06484335RecruitingPhase 1
HIV vaccine study with treatment pause for Thai adults
This study tests whether adding an experimental vaccine can help your immune system control HIV during a temporary break from your antiretroviral therapy (ART). If you have been on ART since shortly after infection with a suppressed viral load, this trial could help you understand if a 'functional cure' is possible.
Pathum Wan, BangkokAges 18–60 - NCT06472245RecruitingPhase 3
Cancer vaccine for lung cancer that stopped responding to immunotherapy
This trial tests a therapeutic cancer vaccine called OSE2101 for people with advanced non-small cell lung cancer whose tumors stopped responding to an immunotherapy drug. The vaccine is designed to help your immune system fight the cancer in a different way.
Beverly Hills, CaliforniaAges 18 years+ - NCT06414057Recruiting
HPV study for women at higher risk in Scotland
This study looks at ways to improve cervical cancer prevention for women in Scotland who face extra challenges, such as addiction, homelessness, prison, or sex work. It includes a vaccination and screening part, plus an interview to hear your views.
EdinburghAges 25–45 - NCT06414733RecruitingPhase 1
Vaccine for advanced breast or esophageal cancer
This trial tests a vaccine that targets HER2 protein on cancer cells. It is for people with advanced breast or esophageal cancer whose tumors have certain markers. The vaccine may help your immune system fight the cancer.
Indianpolis, IndianaAges 18 years+ - NCT05807035RecruitingPhase 1
Personalized vaccine made from your tumor tissue
This Phase 1 trial tests a personalized (autologous) vaccine made from your own tumor tissue. It’s designed for people with advanced cancers who have already had at least one treatment and may still have options for getting tumor tissue for the vaccine.
Adelaide, South AustraliaAges Any age - NCT06381739RecruitingPhase 2
New inhaled COVID-19 booster vaccine trial
This trial tests a next-generation COVID-19 vaccine given as an inhaled mist. It is for adults who have already had at least 3 doses of an mRNA COVID vaccine and are looking for a potentially stronger or longer-lasting immune response.
Halifax, Nova ScotiaAges 18–65
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Common questions
- Are there clinical trials for vaccination?
- Yes. Clin2 currently lists 575 recruiting vaccination studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccination trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccination trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.