Clinical trials
Vaginal Atrophy clinical trials
Below are recruiting vaginal atrophy clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07024667Recruiting
Laser treatment study for vaginal atrophy symptoms
This trial tests a carbon dioxide laser (FemiLift) to see if it can help women with vaginal dryness, burning, itching, or pain during sex caused by menopause. It aims to improve symptoms without hormones.
HaderaAges 45–75 - NCT06828640Recruiting
Vaginal dilator for menopause-related dryness
This trial tests whether using a vaginal dilator (a gentle, cone-shaped device) can help with vaginal dryness, burning, or pain caused by menopause or breast cancer treatments. It adds to your usual care.
Brussels, Brussels CapitalAges 18–85 - NCT05953090Recruiting
Vaginal irritation study with device use and long follow-up
This trial studies a treatment for long-lasting vaginal/vulvar irritation caused by conditions like vaginal atrophy or certain skin conditions of the vulva. You would try the study product/device and be followed over time to see how symptoms recover.
Birmingham, AlabamaAges 18 years+ - NCT06726746Recruiting
Laser treatment for vaginal dryness after menopause
This study tests if a fractional CO2 laser can safely improve vaginal atrophy symptoms like dryness, irritation, or pain during sex in postmenopausal women. It offers a non-hormonal option for those who haven't used hormone therapy or vaginal products recently.
CairoAges 45–65 - NCT05335317Recruiting
Low-intensity laser for vaginal thinning and irritation
This trial studies whether a low-intensity nanosecond laser can improve vaginal atrophy (vaginal thinning) and related symptoms. It may help reduce discomfort for people who fit the study conditions and can complete the required visits and procedures.
Nizhny NovgorodAges 40–75 - NCT06197568RecruitingPhase 2
Study of AZU-101 cream for vaginal dryness in menopause
This study tests an experimental vaginal cream (AZU-101) for postmenopausal women who have vaginal dryness and pain during sex. The goal is to see if it can improve these symptoms without the risks of hormone treatments.
Saint Paul, MinnesotaAges 45–60 - NCT05457972RecruitingPhase 4
Using vaginal estrogen to support breastfeeding after delivery
This study tests whether using estrogen placed in the vagina after childbirth can help breastfeeding or milk pumping go more smoothly. It’s aimed at people who are at least 6 weeks postpartum and plan to breastfeed or pump.
Cleveland, OhioAges 18–50 - NCT04807894RecruitingPhase 4
Vaginal testosterone to prevent repeat UTIs in postmenopausal women
This study tests whether putting testosterone in the vagina can help prevent future bladder infections (UTIs) compared with a dummy treatment. It’s for older postmenopausal women who keep getting UTIs, especially those who can’t or don’t want to use vaginal estrogen.
Brooklyn, New YorkAges 60–90 - NCT06822582Recruiting
Pelvic health rehab after breast or gynecologic cancer
This trial tests a pelvic health rehabilitation program for people who have had breast or gynecologic cancer. It aims to help with pelvic floor problems like bladder or bowel issues that can start during or after treatment.
Edmonton, AlbertaAges 18 years+ - NCT06900374Recruiting
Radiofrequency treatment for vaginal dryness in breast cancer patients
This trial tests if a gentle radiofrequency treatment can help breast cancer patients with vaginal dryness that hasn't improved with standard moisturizers. It aims to improve comfort and quality of life.
LilleAges 40 years+ - NCT07160504RecruitingPhase 4
Vaginal estrogen's effect on blood clotting in postmenopausal women
This trial tests if low-dose vaginal estrogen tablets affect blood clotting in postmenopausal women with vaginal atrophy. It includes women both with and without a past blood clot to see if the treatment is safe.
Aarhus NAges 50 years+ - NCT05379153RecruitingPhase 3
Laser treatment for vaginal dryness after breast cancer
This Phase 3 study tests laser therapy to treat bothersome vaginal dryness (with or without pain during sex) in women who have finished breast cancer treatment. If you qualify, you may receive the study laser procedure to see if it improves symptoms compared with standard care.
Ann Arbor, MichiganAges 22 years+ - NCT05974449RecruitingPhase 2
Probiotics for vaginal dryness in young breast cancer patients
This Phase 2 study tests Lactobacillus vaginal capsules to treat vaginal dryness and tissue changes during breast cancer treatment. It may help by improving vaginal health while you are receiving chemotherapy and ovarian-protecting medicines.
Nanjing, JiangsuAges 18–45 - NCT06962345Recruiting
Testing a new vaginal gel for menopause symptoms
This trial is testing a new non-hormonal gel for vaginal dryness and discomfort after menopause. It aims to see if the gel improves quality of life.
Madrid, MadridAges 40–70 - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+
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Common questions
- Are there clinical trials for vaginal atrophy?
- Yes. Clin2 currently lists 15 recruiting vaginal atrophy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaginal atrophy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaginal atrophy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.