Clinical trials
Muscle Atrophy clinical trials
Below are recruiting muscle atrophy clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06253104Recruiting
Tracking muscle changes in acute heart failure
This study measures how thigh muscles change in people hospitalized with severe heart failure. It aims to understand muscle loss during this condition and how it relates to recovery.
Boston, MassachusettsAges 18–100 - NCT07531719Recruiting
Risdiplam treatment study for type I and II spinal muscle atrophy
This study follows children with spinal muscular atrophy (SMA)—a genetic condition causing muscle weakness—who are being treated with a medicine called risdiplam. Researchers want to understand how well the treatment works and how it affects daily life in young patients.
CairoAges Up to 5 years - NCT05206838Recruiting
Treating gluteus medius tendon weakness after hip replacement
This trial looks at treating a specific hip muscle-tendon problem (gluteus medius insufficiency) after total hip replacement. It may help people who have had ongoing limping despite surgery by using an Achilles tendon–based approach.
MölndalAges 40–80 - NCT05216666Recruiting
Surgery type and leftover limping after hip replacement
This study looks at whether the kind of hip surgery approach affects how much limping remains after a total hip replacement. You may benefit by helping researchers find the approach that leads to better walking after surgery.
MölndalAges 40–80 - NCT06631053Recruiting
Exercise program for 30 days of leg muscle disuse
This study looks at how a specific exercise program affects your muscles after a period of not using them (simulated by a leg brace). You'll wear a brace on one leg for 30 days and do certain exercises to see if they help prevent muscle loss.
Lexington, KentuckyAges 35–45 - NCT03761446Recruiting
Testing how diabetes affects muscle loss after bed rest
This study looks at how pre-diabetes or type 2 diabetes may change skeletal muscle loss and recovery in older adults after a period of bed rest. It may help researchers understand why recovery can be slower and how to better protect muscle in people as they age.
Orlando, FloridaAges 60–80 - NCT05414292Recruiting
Testing rapamycin effect on exercise muscle function in older adults
This study looks at how rapamycin (a medication that affects a growth signal in the body) changes muscle responses when older adults do resistance exercise. It may help researchers understand whether this treatment could improve or alter muscle function with aging.
DerbyAges 50–90 - NCT06185179RecruitingEarly Phase 1
Metformin for muscle recovery in older adults
This study tests whether a common diabetes medicine called metformin can help your muscles recover faster after a minor injury. You may qualify if you are 60 or older, generally healthy, and not taking certain medicines.
Salt Lake City, UtahAges 60 years+ - NCT07069426Recruiting
Protein and muscle loss during leg immobilization
This study tests how different amounts of dietary protein affect your muscles when your leg is temporarily immobilized in a brace. If you are a healthy, active adult, you might help researchers learn how to prevent muscle loss during periods of reduced activity.
Natick, MassachusettsAges 17–39 - NCT04875052Recruiting
Study vibration after ACL injury and future arthritis risk
This study looks at whether using vibration after an ACL injury helps predict or reduce the risk of developing post-traumatic osteoarthritis (wear-and-tear arthritis) later. It may help researchers learn which patients are more likely to develop arthritis after ACL reconstruction.
Chapel Hill, North CarolinaAges 16–35 - NCT06964438Recruiting
Post-surgery electrical muscle stimulation study for colorectal or stomach cancer
This trial tests if using a mild electrical device on your legs after surgery can help you recover faster. It is for people with colorectal or stomach cancer who are having curative abdominal surgery.
Derby, DerbyshireAges 18 years+ - NCT06994689Recruiting
Measuring muscle in COPD patients starting rehab
This trial uses a special device to measure muscle mass and stiffness in the thigh to see if it helps track recovery during pulmonary rehabilitation for COPD.
Le HavreAges 18 years+ - NCT05174611RecruitingPhase 2
Vitamin D to strengthen the thigh after ACL surgery
This Phase 2 study tests whether taking vitamin D can improve thigh (quadriceps) muscle strength after ACL reconstruction. It targets people with low vitamin D levels that persist after surgery and weaker thigh strength on the injured side.
Hong KongAges 18–40 - NCT05919940Recruiting
Testing a muscle stimulation and extra protein plan in ICU patients
This trial tests whether electrical muscle stimulation plus extra protein (protein substitute) can improve muscle health and metabolism in critically ill adults in the ICU. If you’re newly admitted and expected to stay on a breathing machine for several days, it may help you keep more muscle strength during recovery.
Vienna, State of ViennaAges 18 years+ - NCT07597850RecruitingPhase 2
TCM formula versus HMB supplement for muscle strength in older adults
This study compares a traditional Chinese medicine formula with HMB (a muscle-building supplement) to see which helps preserve muscle strength and bone health in adults aged 65 and older who are starting to show signs of frailty. Both treatments aim to help you stay stronger and more active as you age.
TaipeiAges 65 years+ - NCT07161973Recruiting
Beetroot for preventing muscle loss in healthy men
This study tests if a natural substance (nitrate) from beets can help prevent muscle loss in young men when a leg is immobilized. You would stay at a research center for about 10 days with one leg in a cast to simulate a temporary injury.
Indianapolis, IndianaAges 18–44 - NCT05627440Recruiting
Protein diet program to improve muscle strength in heart failure
This trial tests whether adding dietary protein can help skeletal muscles recover and function better in people living with heart failure. It may help with strength, muscle wasting, and overall ability to do daily activities.
Boston, MassachusettsAges 18–100 - NCT07847424Recruiting
Daily heat therapy for people reducing physical activity
This study tests whether daily heat therapy (sauna sessions) can help maintain fitness and health when people temporarily reduce their physical activity. If you are a healthy adult, you might be able to join and contribute to understanding how heat affects the body.
Provo, UtahAges 18 years+ - NCT07843095Recruiting
Protein supplement for muscle health during menstrual cycle
This study tests whether taking a protein supplement during the luteal phase of your menstrual cycle can help prevent muscle breakdown. It may help women who want to maintain muscle strength and understand how their cycle affects their body.
Conroe, TexasAges 18–35 - NCT06573086Recruiting
Resistance training, detraining, and retraining
This study looks at how your body responds to resistance training, a break from training, and then training again. It is for healthy adults who already completed a previous exercise study.
Jyväskylä, Central FinlandAges 18–50 - NCT07179042Enrolling by invitationEarly Phase 1
Metformin for hip fracture recovery in older adults
This study tests whether the diabetes drug metformin can help older adults recover better after hip fracture surgery. To join, you need to be 60+, have had a low-energy hip fracture fixed within 3 days, and be generally healthy without diabetes or kidney issues.
Salt Lake City, UtahAges 60–90 - NCT07171346Enrolling by invitation
Muscle stimulator after ACL reconstruction
This study tests whether a special muscle-stimulating device worn after ACL reconstruction surgery can help your knee recover strength faster. If you qualify, you will use the device at home for a few weeks and your recovery will be checked regularly.
Kansas City, KansasAges 15–50 - NCT06607913Recruiting
Exercise after hospitalization for kidney patients
This study tests whether a personalized exercise program can help adults over 55 with chronic kidney disease regain strength and mobility after a hospital stay.
Aurora, ColoradoAges 55 years+ - NCT06492057Enrolling by invitation
EMS muscle training for astronauts in space
This trial tests if a special muscle stimulation device called EMS can help astronauts stay fit during spaceflight. It may prevent muscle loss in zero gravity.
Mitte, State of BerlinAges 40–60
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Common questions
- Are there clinical trials for muscle atrophy?
- Yes. Clin2 currently lists 36 recruiting muscle atrophy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle atrophy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle atrophy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.