Clinical trials
White Matter Disease clinical trials
Below are recruiting white matter disease clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07108712Recruiting
Using brain MRI to detect early white matter disease
This trial studies whether a special type of MRI can find brain white matter changes early. It might help people who have early symptoms or are at risk for diseases affecting the brain's wiring.
CairoAges 18–80 - NCT07042633Recruiting
Gamma brain waves and memory in small vessel disease study
This study looks at how brain waves in certain areas may affect memory in people with cerebral small vessel disease. It uses EEG, a safe way to measure brain activity, along with imaging and thinking tests, to understand why some people have memory trouble.
Beijing, Beijing MunicipalityAges 55–75 - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03624374Recruiting
Study of LBSL in people with DARS2 mutations
This trial is a natural history study, meaning it tracks how LBSL (a genetic condition) affects the brain, brainstem, and spinal cord over time. It may help researchers better understand disease patterns and provide information that could support future treatments.
Baltimore, MarylandAges Any age - NCT05757141RecruitingPhase 1/Phase 2
Study of fosigotifator for vanishing white matter disease
This early-phase study tests fosigotifator in people with vanishing white matter disease (VWM). The goal is to see whether the treatment is safe and could affect how the disease works in the body and brain.
Boston, MassachusettsAges 6 months+ - NCT03333200Recruiting
Study of genetic brain diseases over time
This trial follows people with genetic neurodegenerative (brain-wasting) disorders over time to better understand how the condition changes. The goal is to learn patterns that could help future treatments or care plans.
Pittsburgh, PennsylvaniaAges Any age - NCT05848271Recruiting
Natural history study for people with HPDL gene changes
This study follows people who have an HPDL gene change to better understand how symptoms and health progress over time. It may help clinicians learn more about the condition and plan future treatments.
San Diego, CaliforniaAges Any age - NCT06715007Recruiting
Study on blood thinners and artery health for small vessel stroke
This study tests whether a combination of antiplatelet drugs and artery-stabilizing medication can improve recovery after a small stroke caused by damage to tiny blood vessels in the brain. It may help prevent further strokes and support healing.
Nanjing, JiangsuAges 30–79 - NCT04753970RecruitingPhase 1/Phase 2
Study uses retina changes to assess blood vessel health
This study looks at the back of your eyes (the retina) to see if it reflects blood vessel health in the brain. It may help doctors find easier ways to track conditions related to small blood vessel disease.
Jacksonville, FloridaAges 18 years+ - NCT06010511Recruiting
White matter changes and brain fluid study in older adults
This study uses special MRI scans to look at white matter changes in the brain (often linked to memory problems). It may help doctors understand more about these changes in older adults visiting memory or geriatric clinics.
LeidenAges 65 years+ - NCT06179680Recruiting
White matter changes in memory problems or Alzheimer's
This study uses brain MRI scans to look at white matter changes in people with memory problems (amnestic mild cognitive impairment) or Alzheimer's disease. It aims to understand how these changes relate to memory loss.
San Donato Milanese, MilanoAges 65 years+ - NCT04073966Recruiting
MRI markers for memory changes after brain radiation
This study uses MRI scans to look at how radiation treatment for newly diagnosed brain metastases affects thinking and memory. It aims to understand the effects better, which may help guide future treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT07103681Recruiting
Brain scan study for normal pressure hydrocephalus
This study looks at brain scans and spinal fluid in people with normal pressure hydrocephalus (NPH) to understand how it affects thinking and walking. If you have NPH and are 60 or older, this research may help find better ways to diagnose and treat you.
LondonAges 60 years+ - NCT04415372Enrolling by invitation
MRI brain scan study for white and gray matter in MS
This study uses detailed MRI scans to look at brain “white matter” and “gray matter” changes in people with multiple sclerosis (MS). It may help researchers better understand how MS affects the brain and relates to symptoms.
Madison, WisconsinAges 18–60 - NCT02669797Enrolling by invitation
Family-based program to help families eat dinner together
This study offers an intervention focused on family dinners to help children improve their eating habits. It targets children who eat family dinners rarely and have a higher weight range, to see if the program can help improve health over time.
Aurora, ColoradoAges 5–10
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Common questions
- Are there clinical trials for white matter disease?
- Yes. Clin2 currently lists 15 recruiting white matter disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a white matter disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a white matter disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.