Clinical trials
Youth clinical trials
Below are recruiting youth clinical trials, each written for real people, not researchers. We’re tracking 247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04729504Recruiting
Caregivers of young children with anxiety for a new program
This study adapts an anxiety-helping program so it fits families better. You may be invited to take part as a caregiver of a child ages 4 to 10.
Miami, FloridaAges 18 years+ - NCT06651554Recruiting
Suicide prevention app study for teens in Bogota
This trial tests a digital platform designed to help prevent suicide among teenagers. It aims to make mental health support more accessible for students in Bogota schools.
Bogotá, ColombiaAges 14–19 - NCT05031364Recruiting
CBT skills coaching for youth with autism and emotional needs
This study tests a therapy program (called CBT) that helps children with autism who also struggle with emotional or behavioral regulation. It aims to reduce emotional outbursts and improve coping while receiving care through community providers.
Culver City, CaliforniaAges 6–14 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05078164Recruiting
Hospital program to prevent future firearm harm in youth
This trial tests a hospital-based prevention program for youth ages 10–17 who were hurt by violence, especially firearm-related injuries. It aims to connect families with support to reduce the chance of future harm. You and a caregiver work together in the program after the hospital visit.
Richmond, VirginiaAges 10–17 - NCT05125822Recruiting
Study of how bodies change weight in youth with obesity
This study looks at what helps or drives weight changes in children and teens with obesity. You may be asked about growth and body changes to better understand why weight changes happen and how to manage them.
Chicago, IllinoisAges 11–15 - NCT05153369Recruiting
DBT-based care for youth at risk for bipolar disorder
This study tests a structured, “DBT-informed” care program for young people who either have bipolar disorder or are at family risk for it. It may help by offering closer, organized support aimed at preventing or reducing mood problems.
Toronto, OntarioAges 13–23 - NCT05153382Recruiting
Dialectical behavior therapy for youth at bipolar risk
This trial tests whether a structured therapy called dialectical behavior therapy (DBT) helps young people with bipolar disorder or at risk for it, especially with self-harm or risky behaviors. It may help by teaching coping skills and improving safety and emotional control.
Toronto, OntarioAges 13–23 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT05336201RecruitingPhase 2
Brain training program for teens with sickle cell disease
This Phase 2 study tests a cognitive (thinking) training program to help teens with sickle cell disease prepare for the changes in their care as they grow older. It may help with skills like learning, attention, and planning for transition to adult care.
Birmingham, AlabamaAges 10–18 - NCT05415007Recruiting
Support program for parents and teens after a new cancer diagnosis
This study tests a brief program meant to reduce anxiety and build resilience in families when a child was newly diagnosed with cancer. It involves both the parent and the child (ages 8–17) and requires consent/assent and English ability.
San Francisco, CaliforniaAges 8–18 - NCT05451524Recruiting
Preventing insomnia in teens with family history
This study aims to prevent insomnia in young people who already have mild sleep problems and have a parent with a history of insomnia. You may qualify if your sleep symptoms happen occasionally, but you do not have a diagnosed sleep disorder or certain other mental health or medical issues.
Shatin, NTAges 15–24 - NCT05454176RecruitingPhase 4
Diabetes monitoring support for African youth with type 1
This study helps children and young adults with type 1 diabetes in Uganda improve how their diabetes is tracked, likely by using an additional monitoring sensor. If you join, you’ll be asked to attend regular pediatric diabetes clinic visits and use the study monitoring device for part of the start period.
Minneapolis, MinnesotaAges 4–26 - NCT05457140Recruiting
Testing genes and other samples in youth with first psychosis
This study looks at many types of tests (including genetic testing and other lab data) to help understand what may be causing first-time psychosis symptoms in youth. It may help doctors learn more about the condition for future care, and it can involve analyzing family genetic information.
San Diego, CaliforniaAges 7–17 - NCT05471232Recruiting
Genomic testing for youth mental health crises with IDD
This study looks at genetic (DNA) information to understand mental health crises in youth with intellectual and developmental disabilities. It may help doctors learn why these crises happen and improve how future families are supported.
San Diego, CaliforniaAges 7–17 - NCT05477134Recruiting
Arginine metabolism study in teens with type 2 diabetes
This study looks at how the body uses a nutrient called arginine in young people with type 2 diabetes and compares them to healthy peers. It may help researchers understand metabolism changes in diabetes and guide future treatments.
Houston, TexasAges 12–20 - NCT05528471Recruiting
Test whether fructose affects fatty liver in teens
This study looks at how fructose (a type of sugar) may affect fatty liver disease (NAFLD) in teens with obesity. The goal is to learn whether fructose changes liver health, using MRI/MRS scans to measure the liver.
Edmonton, AlbertaAges 12–18 - NCT05627492Recruiting
DBT booster sessions for youth at bipolar risk
This study adds short “booster” sessions to Dialectical Behavior Therapy (DBT) for young people who already took part in a prior DBT study, including those with bipolar symptoms or strong family risk. It aims to see if extra DBT support helps mood and coping over time.
Toronto, OntarioAges 14–25 - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05765864Recruiting
Study of self-harm in at-risk teens
This study looks at self-harm and thoughts/behaviors related to safety in teenagers who are considered at higher risk. It may help researchers better understand what supports are needed for teens who self-harm without wanting to die.
LjubljanaAges 13–18 - NCT05788783Recruiting
6-week dog training program for youth in outpatient mental health care
This study tests whether a structured dog training program is practical and helpful for youth who are already getting outpatient mental health services. You may be able to participate in a 6-week program if you can attend every week and have no safety concerns with dogs.
Chicago, IllinoisAges 8–17 - NCT05819853RecruitingPhase 3
Semaglutide to help restart periods in PCOS
This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.
Aurora, ColoradoAges 12–35 - NCT05848570Recruiting
Digital program for reducing HIV risk in SGM youth
This trial tests a digital health program (available with limited in-person contact) to help SGM young people reduce their risk of HIV. You may be a good fit if you’re in the right age range and have had certain types of sex in the last 6 months.
Chicago, IllinoisAges 13–34 - NCT05894772Recruiting
Virtual portal program for youth waiting for chronic pain care
This study tests a virtual “stepped care” portal (a website/app) to help young people manage chronic pain while they’re waiting to start specialized care. It aims to see whether the portal improves support and outcomes during the wait time.
Halifax, Nova ScotiaAges 12–18
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Common questions
- Are there clinical trials for youth?
- Yes. Clin2 currently lists 247 recruiting youth studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a youth trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a youth trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.