Treatment
Chlorhexidine clinical trials
We’re tracking 51 recruiting studies that include Chlorhexidine, each written for real people, not researchers, below.
Recruiting studies
- NCT06689176Recruiting
Chlorhexidine wash during bladder removal surgery
This trial tests a special antibacterial wash (chlorhexidine) applied to a piece of intestine used to create a new way for urine to leave the body after bladder removal. It aims to reduce infections and improve recovery.
New York, New YorkAges 18 years+ - NCT06692582Recruiting
Saltwater rinse for treating gum disease
This study tests whether rinsing your mouth with a special saltwater solution (electrolyzed water) can help treat gum disease. It's for people who have advanced gum disease and want to try a simple, gentle addition to regular care.
LjubljanaAges 18–80 - NCT06627270RecruitingPhase 2
Antibiotics before surgery for oral cancer
This trial tests if taking antibiotics and using a mouth rinse before surgery can help treat oral cancer by targeting bacteria inside the tumor. It is for people with a new diagnosis of oral cancer who are scheduled for surgery.
Cleveland, OhioAges 18 years+ - NCT07142408RecruitingPhase 3
Bacteria reduction before skin cancer surgery on legs
This trial tests if reducing bacteria on your skin before skin cancer surgery on the leg can lower the risk of infection, especially for wounds left open to heal naturally.
Marlton, New JerseyAges 18 years+ - NCT06587880RecruitingPhase 4
Mouthwash and wisdom tooth extraction recovery
This study compares different mouthwashes to see which one helps healing after wisdom tooth surgery. If you have a lower wisdom tooth that is impacted (stuck) and need it removed with some bone cutting, you may qualify.
AmmanAges 18 years+ - NCT06505759RecruitingPhase 1
Bromelain gel vs. chlorhexidine for gum disease treatment
This trial tests if a gel made from bromelain (a pineapple enzyme) works as well as a standard antibiotic gel to treat gum pockets caused by periodontitis. It may offer a gentler option for patients with moderate gum disease.
Bengaluru, KarnatakaAges 30–50 - NCT06464770Recruiting
Improving infection prevention before shoulder surgery
This study compares different ways to clean the skin before shoulder surgery to prevent infection. It might help if you are going to have shoulder surgery and want safer, more effective infection prevention.
Seattle, WashingtonAges 18–89 - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT06339203Recruiting
Saline vs. special antiseptic for c-section wound cleaning
This study compares cleaning the wound with plain salt water versus a diluted antiseptic solution after a planned C-section. The goal is to see which method better prevents infections for mothers with certain health conditions.
Loma Linda, CaliforniaAges 18 years+ - NCT06163469Recruiting
Chlorhexidine bladder wash for people with long-term suprapubic catheters
This study tests whether washing the bladder with a solution called chlorhexidine (a germ-killer) can lower the number of unplanned hospital visits and improve quality of life for people who have a long-term suprapubic catheter. You may be eligible if you have had a catheter for at least a year and have had a recent urinary tract infection.
New Haven, ConnecticutAges 18 years+ - NCT06126614RecruitingPhase 3
Infection prevention in joint replacement surgery
This trial tests a way to prevent infections for people getting a hip or knee replacement. It compares different methods to see which works best and may help lower your risk of infection after surgery.
Hamilton, OntarioAges 18 years+ - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT05679661Recruiting
Immunity-focused nutrition before surgery to reduce lung infections
This study gives an immunity-supporting nutrition plan and an oral cleaning product before and around surgery to help older adults avoid breathing-related complications. It is mainly for people at higher risk of post-surgery lung problems, and it checks whether the approach is safe and helpful.
BeijingAges 65 years+ - NCT05586776RecruitingPhase 4
Using skin cleaning to prevent post-surgery wound infections
This trial tests a “skin decolonization” routine using medicated skin cleaning to help lower the risk of surgical site infections after abdominal surgery. You may be eligible if you recently had an open abdominal incision and your wound is healing as expected at discharge.
Newport Beach, CaliforniaAges 18 years+ - NCT03384537RecruitingEarly Phase 1
Tropolone mouthwash test in healthy adults
This early trial compares a mouthwash that contains tropolone versus a mouthwash without tropolone to see how well each works against germs in the mouth. You may be asked to pause your usual mouth-cleaning routine for a few days beforehand.
CairoAges 18–45 - NCT07104084Recruiting
Antiseptic wash and wound healing after hip replacement
This study tests whether using a special antiseptic wash during hip replacement surgery affects how well the wound heals. It may help doctors choose safer ways to clean the skin before your operation.
Monroeville, PennsylvaniaAges 18 years+ - NCT07555366Recruiting
Healing after tooth extraction: two treatment approaches
This study compares two treatments applied to the socket (the hole left after a tooth is removed) to help it heal better. One treatment uses a product called microRepair, and the other uses chlorhexidine, a common antimicrobial rinse. The goal is to see which helps the extraction site heal faster and with fewer problems.
Roma, RMAges 18–75 - NCT07191262Recruiting
Comparing mouth rinses after tooth extraction and bone graft
This study compares three different mouth rinses (one with EDTA, one with chlorhexidine, and one with essential oils) after tooth extraction and bone grafting. It aims to find which rinse helps keep the area clean and promotes healing.
Birmingham, AlabamaAges 18–85 - NCT07239219Recruiting
Testing a special rinse to prevent infection after catheter removal
This trial tests whether using a special antiseptic solution (Irrisept) when removing a urinary catheter can lower the chance of getting a urinary tract infection. It is for people visiting a urology clinic for catheter removal who are not already on antibiotics.
Columbus, OhioAges 18 years+ - NCT07696364Recruiting
Testing a mouthwash for gum health
This trial tests a special mouthwash (chlorhexidine) to see how well it prevents gum inflammation. It compares a standard version to one that also reduces tooth staining. You may be eligible if you are healthy, do not smoke, and have at least 24 teeth with healthy gums.
Bern, Canton of BernAges 18–40 - NCT07453069RecruitingPhase 2
FB301 for women with vaginal imbalance and prior failed embryo transfer
This study tests whether a vaginal gel (FB301) can improve the balance of bacteria in the vagina for women who have had a failed frozen embryo transfer. If you are planning another frozen embryo transfer and have a specific vaginal bacteria imbalance, this trial may help you.
Wichita, KansasAges 18–40 - NCT07124650RecruitingPhase 4
Sore throat after neck surgery study
This study tests if a special spray can help prevent or reduce sore throat after thyroid or parathyroid surgery. It may help you feel more comfortable after your operation.
Saint PetersburgAges 18 years+ - NCT07429812Enrolling by invitation
Chitosan-Chlorhexidine Gel for Healing After Tooth Extraction
This trial tests a gel made from chitosan and chlorhexidine to see if it helps heal wounds faster after tooth removal in people with diabetes.
Al KharjAges 20–50 - NCT07529444Recruiting
Cleaning methods for infected dental implants
This study compares different cleaning methods for dental implants that have an infection around them (peri-implantitis). It aims to find the best way to clean the implant surface to help it heal and be preserved.
ZagrebAges Any age
Common questions
- Are there clinical trials studying Chlorhexidine?
- Yes. Clin2 currently lists 51 recruiting studies that include Chlorhexidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Chlorhexidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Chlorhexidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Chlorhexidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.