Treatment
Chlorhexidine clinical trials
We’re tracking 53 recruiting studies that include Chlorhexidine, each written for real people, not researchers, below.
Recruiting studies
- NCT07481955RecruitingPhase 2
A study of chlorhexidine and metronidazole plus FB301 for bacterial vaginosis
This trial tests a pre-treatment with chlorhexidine and/or metronidazole before a new drug called FB301 in women with bacterial vaginosis (BV). It aims to see if this combination is safe and works well.
Berlin, State of BerlinAges 18–45 - NCT06219226Enrolling by invitation
Mouthwash for bad breath study
This study tests if two special mouthwashes, chlorine dioxide and chlorhexidine, can reduce bad breath. You'd be asked to use one of these rinses and have your breath checked.
Budapest, BudapestAges 18 years+ - NCT07559877RecruitingPhase 3
Chlorhexidine spray to prevent radiation skin damage in throat cancer
This study tests whether a chlorhexidine spray (an antiseptic liquid) can prevent or reduce skin damage caused by radiation therapy in people being treated for nasopharyngeal cancer (cancer in the back of the nose/throat). Radiation dermatitis—painful redness and irritation of the skin—is a common side effect, and this spray may help protect your skin during treatment.
Nanchang, JiangxiAges 18–75 - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT07321704Recruiting
Irrisept vs. Saline for Pilonidal Flap Surgery
This study compares two types of wound cleaning solutions used during surgery for pilonidal disease: an antiseptic called Irrisept (0.05% chlorhexidine gluconate) versus normal saline. The goal is to see if Irrisept helps prevent infection and improve healing after a flap-based closure procedure.
Los Angeles, CaliforniaAges 18 years+ - NCT07198919Enrolling by invitationPhase 1/Phase 2
Pain relief during root canal for infected tooth: gel vs. antibiotic paste
This trial compares two medicines placed inside a tooth after root canal cleaning to see which reduces pain better between appointments. If you have an infected single-root tooth and are between 16-45 years old, you may be able to join.
Karachi, SindhAges 16–45 - NCT07672847Enrolling by invitation
Denture cleaners and their effect on milled denture materials
This study tests how different denture cleaning solutions affect the surface of two special types of denture materials (PMMA and PEEK) that are made by computer-controlled milling. It aims to see if these cleaners cause wear or damage over time.
Shibīn al KawmAges Any age - NCT04256798RecruitingPhase 3
Respiratory care after high-risk abdominal surgery
This trial looks at a breathing-focused care plan given around the time of major abdominal surgery to improve recovery and outcomes. You may be eligible if you’re having a large midline abdominal incision and can be followed after surgery.
Botucatu, São PauloAges 10–100 - NCT06284174Recruiting
Comparing two antiseptics for spinal surgery wound soaking
This trial compares two common antiseptics (povidone-iodine and chlorhexidine gluconate) to see which better reduces germs in spinal surgery wounds during the operation. If you are having lumbar spine surgery, this study may help determine the best way to prevent infections.
Tainan, TaiwanAges 18 years+ - NCT06720064Recruiting
Chlorhexidine dressing care for port and central catheters in children
This trial tests whether a special care bundle with a germ-killing dressing can reduce infections in children with port or central line catheters. It may help keep your child safer during treatment.
IzmirAges 1–17 - NCT06869096Recruiting
Flushing liquid during colorectal cancer surgery
This trial compares two different liquids used to flush the surgical area during colorectal cancer surgery to see which one better prevents infections. If you are having surgery for colorectal cancer, you may be able to join.
Nanchong, SichuanAges 18–85 - NCT06967402Recruiting
Mouthwash study for gum disease treatment
This study tests two types of mouthwash to see which helps treat gum disease better when used with regular dental care. It may be a good option if you have moderate to severe gum disease and are generally healthy.
Hong KongAges 18 years+ - NCT07172009Recruiting
Does chlorhexidine mouthwash affect blood sugar after meals?
This trial tests whether using chlorhexidine mouthwash changes how your body handles sugar after eating. It may help us understand a new way to manage blood sugar levels.
Plymouth, DevonAges 18 years+ - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT07311512Recruiting
Gum treatment and mouthwash study for gum disease
This trial tests if a professional gum cleaning combined with a special mouthwash can improve gum health and blood vessel function. It may help people with early gum disease who haven't had recent gum treatment.
Portsmouth, HampshireAges 30–75 - NCT07421323Recruiting
Hand cleaning study for premature babies in the NICU
This study tests if a special hand-cleaning method using chlorhexidine and alcohol can help prevent infections in premature babies (born before 37 weeks) in the newborn intensive care unit (NICU). It aims to see if this cleaning approach is better than the usual method for keeping babies safe from hospital-acquired infections.
AlexandriaAges 6 hours–1 day - NCT07609797Recruiting
Fluoride and Mouthwash Effects on Cavity Markers in Children
This study tests whether sodium fluoride and chlorhexidine (a prescription mouthwash) change certain markers in saliva that may relate to tooth decay in children with cavities. The goal is to understand if these common dental treatments affect the body's natural cavity-fighting substances.
Alanya, AntalyaAges 6–8 - NCT07039955Enrolling by invitation
Preventing CPE germ spread in ICU patients
This trial tests whether daily cleansing with a special soap (chlorhexidine) combined with thoughtful use of antibiotics and stomach acid reducers can help prevent the spread of a tough germ called CPE (carbapenemase-producing Enterobacteriaceae) in the ICU. It aims to keep ICU patients safer from infection.
Chuncheon, Gangwon-doAges 19 years+ - NCT06201377Enrolling by invitation
Early healing after periodontal surgery
This trial looks at how well gum surgery incisions heal in the first days and weeks after the procedure. It may help people with gum disease who need surgery to control their condition.
Leioa, BiscayAges 18 years+ - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT07696364Recruiting
Testing a mouthwash for gum health
This trial tests a special mouthwash (chlorhexidine) to see how well it prevents gum inflammation. It compares a standard version to one that also reduces tooth staining. You may be eligible if you are healthy, do not smoke, and have at least 24 teeth with healthy gums.
Bern, Canton of BernAges 18–40 - NCT06627270RecruitingPhase 2
Antibiotics before surgery for oral cancer
This trial tests if taking antibiotics and using a mouth rinse before surgery can help treat oral cancer by targeting bacteria inside the tumor. It is for people with a new diagnosis of oral cancer who are scheduled for surgery.
Cleveland, OhioAges 18 years+ - NCT05971810Recruiting
Oral cleaning and nutrition support around surgery for older adults
This trial studies whether cleaning the mouth before and after major surgery, plus special nutrition support, can lower the risk of breathing complications in older adults. It may help patients who are at higher risk for lung problems around the time of general anesthesia.
Shijiazhuang, HebeiAges 65 years+ - NCT06464770Recruiting
Improving infection prevention before shoulder surgery
This study compares different ways to clean the skin before shoulder surgery to prevent infection. It might help if you are going to have shoulder surgery and want safer, more effective infection prevention.
Seattle, WashingtonAges 18–89
What Chlorhexidine is being studied for
Conditions with recruiting Chlorhexidine studies.
Common questions
- Are there clinical trials studying Chlorhexidine?
- Yes. Clin2 currently lists 53 recruiting studies that include Chlorhexidine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Chlorhexidine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Chlorhexidine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Chlorhexidine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.