Treatment
Comparator clinical trials
We’re tracking 1,733 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT06022419Recruiting
Comparing two treatments for finger fractures
This trial compares two non-surgical treatments for fractures of the finger bone closest to the hand. It will help find out which approach—a special cast or a simple splint—works better for healing.
ViennaAges 18–70 - NCT06074952Recruiting
Color stability of denture teeth in staining solutions
This trial tests how well different acrylic denture teeth keep their color when soaked in various staining liquids. It uses only specific front teeth (maxillary central incisors) that are flat on the surface and made of a special acrylic called IPN.
Karachi, SindhAges Any age - NCT06176534RecruitingPhase 2
Comparing two treatments for advanced breast cancer with low hormone receptor
This trial compares two treatment options for advanced breast cancer that has low hormone receptor levels and is HER2-negative. It tests whether a combination of chemotherapy followed by maintenance therapy works better than a CDK4/6 inhibitor combined with hormone therapy. This is for people who have not had chemotherapy for their advanced disease.
Zhengzhou, HenanAges 18 years+ - NCT05956639RecruitingPhase 3
Rezvilutamide with ADT and chemo: shorter versus longer treatment
This Phase 3 trial compares two lengths of rezvilutamide treatment when given with hormone therapy (ADT) and chemotherapy for men with advanced prostate cancer. It aims to find which treatment duration works best and is safest to help control the cancer.
Nanjing, JiangsuAges 18 years+ - NCT06029374Recruiting
Comparing treatments for hand bone fractures
This trial compares two treatments for a common hand fracture—the boxer's fracture—to see if one is better. It will help people recover quickly without surgery.
ViennaAges 18–70 - NCT05937412Recruiting
Honey or alcohol to disinfect children’s skin
This trial compares honey versus alcohol applied to skin to see which works better as a disinfectant. It involves children with otherwise healthy skin and checks for safe use before and after application.
Cairo, Cairo GovernorateAges 2–12 - NCT06034821Enrolling by invitationPhase 4
ECT vs. ketamine for suicidal depression in adults
This trial compares two treatments—ECT (electroconvulsive therapy, which uses electrical stimulation) and ketamine (a medicine given as a shot)—to see which works better for quickly reducing suicidal depression. It is for adults who are in a severe depressive episode with active suicidal thoughts.
San Francisco, CaliforniaAges 18–90 - NCT05947279Recruiting
Testing noninvasive brain stimulation to study motor control
This study uses noninvasive brain stimulation and related tasks (and may include virtual reality) to understand how the brain controls movement. It may help researchers learn more about motor control, which can guide future treatments.
Richmond, VirginiaAges 18–40 - NCT05873777Recruiting
PET/CT scans to compare two tracers in FAP or SSTR2-positive cancer
This study compares two special PET/CT scan tracers—68Ga-FAPI-LM3 and 18F-FDG—to see how well they detect cancer that shows FAP or SSTR2 signals. It may help doctors choose better imaging to find or assess certain tumors.
Xiamen, FujianAges 18 years+ - NCT05813015RecruitingPhase 3
Testing S-1 after stomach cancer surgery with or without sequence therapy
This Phase 3 study compares two ways of giving S-1 medicine after curative stomach cancer surgery in stage III disease. It aims to see whether the sequential approach improves outcomes while keeping treatment safe.
Hanzhou, ZhejiangAges 18–75 - NCT05788029Enrolling by invitation
Laparoscopic vs open pancreatic surgery for periampullary cancer
This trial compares two ways of doing a major pancreas-and-duodenum operation: laparoscopic (small incisions) versus open surgery (larger incision). It aims to see which approach works better for nonpancreatic periampullary adenocarcinoma when the goal is cure.
Wuhan, HubeiAges 18–75 - NCT05642611RecruitingPhase 3
Cooling and compression for nerve protection during chemotherapy
This study tests whether using cooling and/or compression on the arms or legs can prevent nerve damage that can happen from certain chemotherapy drugs. If you get eligible chemo soon, this may help lower the chance of painful numbness or tingling during treatment.
Birmingham, AlabamaAges 18 years+ - NCT05378087Recruiting
Compare two ways to plan treatment for cervical cancer
This study compares two staging methods—using surgery results versus imaging tests—to help doctors plan treatment for locally advanced cervical cancer. It may improve how accurately the cancer is mapped, which could affect treatment choices and outcomes.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05319067Recruiting
Gut bacteria study in toddlers on long-term reflux antibiotics
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
MontpellierAges 1–3 - NCT05439291Recruiting
Comparing surgery and non-surgery for pilonidal disease
This study compares operative (surgery) versus non-operative (non-surgery) treatment options for pilonidal disease. It may help find which approach works better for people at Stanford Healthcare.
Palo Alto, CaliforniaAges 8 years+ - NCT05538416Recruiting
Back surgery approach trial for mild slip and leg pain
This trial compares a newer, “cortical bone trajectory” method with more traditional open surgery and a minimally invasive approach for treating certain low-back slips. It looks at short-term outcomes to see which approach helps patients recover better and relieve leg symptoms.
GroningenAges 18–75 - NCT05326880Recruiting
Long-term follow-up comparing zirconia and titanium dental implants
This study checks how well two kinds of dental implants (zirconia and titanium) work over 5 years in replacing a single tooth. You may be included if you already received the specific implant type and restoration the study requires and you can attend regular checkups.
DüsseldorfAges 18 years+ - NCT05099341Recruiting
Study blood HDL differences in depression
This study compares a special type of cholesterol in the blood (HDL) between people with depression and people without depression. Researchers want to understand how depression may be linked to differences in HDL and related blood markers.
DijonAges 18 years+ - NCT04992780RecruitingPhase 2
Hypo-fractionated radiation versus standard radiation for lung cancer
This study compares two different radiation schedules for stage III non-small cell lung cancer, both combined with chemotherapy and immunotherapy. It aims to see whether giving radiation in a different way can work as well (or better) and be safe while treating the cancer.
Kansas City, KansasAges 18 years+ - NCT04751409RecruitingPhase 2
Less versus more follow-up after sarcoma surgery
This trial compares two schedules of post-treatment check-ups to see which one better supports patient quality of life. You’d fill out surveys for up to two years to measure how you feel over time.
Houston, TexasAges 18 years+ - NCT05257161Recruiting
Carotid stent study comparing two stent positions using brain MRI
This study looks at how well a carotid artery stent works soon after the procedure, using special MRI pictures of the brain. It compares outcomes between stent placement closer to the top versus closer to the bottom of the narrowed area, to see which approach is safer for early brain effects.
NovosibirskAges 45–80 - NCT04730700Recruiting
Radiofrequency treatment test for facet back pain
This study compares a nerve procedure (radiofrequency “neurotomy” using an expandable electrode) to non-procedure medical care for long-lasting low back pain from facet joints. It aims to see whether the procedure helps more safely than conservative treatment.
Kansas City, KansasAges 18 years+ - NCT04934839Recruiting
Gait study comparing prosthetic walking types in adults
This study compares how people walk using an osseointegrated prosthesis (a prosthesis connected to the bone) versus a traditional socket prosthesis. It may help researchers understand which option works better for walking balance, comfort, and function.
Milan, MIAges 18 years+ - NCT04752761Recruiting
Digital tracking after knee replacement for people with severe knee arthritis
This study checks whether using digital tools (like a phone app or tablet) can better track patient-reported outcomes after knee replacement, compared with usual outpatient follow-up. It may help improve how symptoms and recovery are monitored, which can guide care.
Bologna, ItaliaAges 18–78
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,733 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.