Clin2
NCT07807020Possibly a fitEnrolling by invitation

Lower-dose pain medication for knee replacement surgery

Intrathecal Dexmedetomidine

Part of Pain clinical trials.

This study tests whether a lower dose of a pain medication given through spinal anesthesia can provide good pain relief after knee replacement surgery with fewer side effects. It may help reduce risks like low blood pressure or slow heart rate.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
60 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You must be between 18 and 60 years old.
  • You must be scheduled for a knee replacement surgery.
  • You must be in good physical health (ASA class II or III).
  • You must not have allergies to the study drugs.
  • You must not have heart rhythm problems, neurological disorders, or be pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06837844Recruiting
Pain relief study for knee replacement surgery

This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.

Kafr ash Shaykh, Kafrelsheikh
NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery

This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.

Cairo
NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery

This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.

Tanta, El-Gharbia
NCT06946277Not yet recruiting· Phase 4
Pain relief study for hip replacement surgery

This study tests a medicine called dexmedetomidine to see how well it relieves pain during hip replacement surgery done with spinal anesthesia. It may help improve pain control during and after the procedure.

Beijing, Beijing Municipality
NCT07176065Not yet recruiting· Phase 4
Adding dexmedetomidine to knee injection for total knee replacement pain

This study tests whether adding a sedative medicine called dexmedetomidine to the usual numbing injection around the knee can improve pain relief and recovery after a total knee replacement. It is a pilot (small early-stage) trial to see if this approach is safe and worth studying more.

Kuala Lumpur, Kuala Lumpur
NCT07743853Not yet recruiting
Study of dexmedetomidine for pain after hip replacement

This study tests whether a medication called dexmedetomidine, given through an IV during hip replacement surgery, can help reduce pain and inflammation after surgery. It may help you recover more comfortably.

Poznan

Hear when a new Intrathecal Dexmedetomidine trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.