Treatment
Dupilumab clinical trials
We’re tracking 55 recruiting studies that include Dupilumab, each written for real people, not researchers, below.
Recruiting studies
- NCT06868212RecruitingPhase 3
Testing remibrutinib vs dupilumab for chronic hives
This study compares two oral medications, remibrutinib and dupilumab, to see which works faster for chronic hives that don't get better with standard antihistamines. You may be eligible if you have had hives and itching for at least 6 months and they are still active despite daily antihistamines.
Birmingham, AlabamaAges 18 years+ - NCT06477653RecruitingPhase 2
Dupilumab for hypereosinophilic syndrome with ongoing symptoms
This trial tests if dupilumab, added to your current treatment, can help with remaining symptoms of hypereosinophilic syndrome (HES) like asthma, eczema, nasal polyps, or eosinophilic esophagitis. You may qualify if you're already on a biologic therapy that lowers eosinophils but still have bothersome symptoms.
Bethesda, MarylandAges 18–99 - NCT06637306RecruitingEarly Phase 1
Testing dupilumab with chemo for advanced triple-negative breast cancer
This trial adds dupilumab (a targeted immune treatment) to standard chemotherapy before surgery for patients with advanced triple-negative breast cancer. The goal is to see if this combination helps shrink tumors more effectively.
New York, New YorkAges 18 years+ - NCT06665971RecruitingPhase 4
Dupilumab for esophagus muscle function in EoE
This trial tests if dupilumab, a weekly injection, can improve the muscle function of the esophagus in people with eosinophilic esophagitis (EoE) who haven't gotten better with acid-reducing medications. Researchers want to see if it helps with swallowing and reduces inflammation.
La Jolla, CaliforniaAges 22 years+ - NCT06695897Recruiting
Long-term real-world study of Dupilumab for eosinophilic esophagitis
This study looks at how well Dupilumab works over time in people aged 12 and older with eosinophilic esophagitis (EoE) whose symptoms are not well controlled by standard treatments. It aims to understand the medicine's effects in everyday medical practice.
Dachau, BavariaAges 12 years+ - NCT06705387RecruitingPhase 2
Dupilumab vs steroid for narrow EoE in young people
This study compares two treatments for EoE that has caused narrowing in the esophagus: dupilumab (a biologic injection) versus a topical corticosteroid (a swallowed steroid). It aims to see which works better for teens and young adults to improve swallowing and reduce inflammation.
Aurora, ColoradoAges 12–25 - NCT06389136RecruitingPhase 3
Study of upadacitinib for eczema after dupilumab didn't work
This trial tests if a pill called upadacitinib (a JAK inhibitor) can help adults with moderate-to-severe atopic dermatitis (eczema) that didn't improve enough with dupilumab. You may be able to join if your eczema is still active despite using dupilumab for at least 4 months.
Birmingham, AlabamaAges 18–63 - NCT05263206RecruitingPhase 3
Shot medicine (dupilumab) for severe, unexplained chronic itching
This Phase 3 study tests whether dupilumab injections can reduce severe itching that has no clear cause. It also checks how safe the medicine is over the study period.
Bakersfield, CaliforniaAges 18–90 - NCT06892704Recruiting
Dupilumab smell restoration study for CRSwNP
This study tests if the medication dupilumab can improve smell loss in people with chronic sinusitis and nasal polyps. Researchers will check if blocking in the nose and electrical signals in the brain can predict who will benefit.
Chicago, IllinoisAges 18–65 - NCT07052396Recruiting
Dupilumab for COPD: long-term real-world study
This study looks at how well dupilumab works over time for people with COPD who still have symptoms despite standard treatments and who have a certain type of inflammation (elevated eosinophils). It uses data from regular doctor visits and patient questionnaires to understand real-world benefits and safety.
AuerbachAges 18 years+ - NCT07053423RecruitingPhase 4
Dupilumab for COPD with airway inflammation
This study tests if a drug called dupilumab, given as a shot under the skin, can reduce airway inflammation in people aged 40-85 with moderate-to-severe COPD who also have signs of a specific type of inflammation called Type 2. It may help if you have frequent flare-ups and are already using multiple inhalers.
Birmingham, AlabamaAges 40–85 - NCT07257835Recruiting
Dupilumab for tough stomach and gut diseases
This trial tests if dupilumab can help people with hard-to-treat stomach ulcers linked to eosinophilic gastrointestinal disorders (EGIDs), where a type of white blood cell builds up in the gut. It may offer a new option for those who haven't gotten better with other treatments.
ShanghaiAges 1–18 - NCT07309614RecruitingPhase 3
Dupilumab for asthma remission study
This trial tests whether dupilumab can help people with moderate-to-severe asthma achieve clinical remission. It may be an option if you have asthma with high levels of certain inflammatory markers and have had at least one asthma attack in the last 2 years.
Nedlands, Western AustraliaAges 18–79 - NCT06851403Enrolling by invitation
Dupilumab for children with asthma in China
This study looks at how well and how safely the medicine Dupilumab works for children whose asthma is not well-controlled with their current inhalers. The goal is to see if it can help reduce asthma attacks and improve daily life.
Guangzhou, GuangdongAges 4–16 - NCT06683261Recruiting
Real-world study of biologics for nasal polyps
This study follows people with chronic rhinosinusitis and nasal polyps who are starting a biologic medication (omalizumab, mepolizumab, or dupilumab) to see how well it works in real life.
AalstAges 18 years+ - NCT06234761Recruiting
Study on immune responses in nasal polyps
This trial looks at how the immune system reacts in people with nasal polyps. It may help doctors better understand and treat this condition.
GhentAges 18 years+ - NCT03936335Recruiting
Study women with atopic dermatitis during pregnancy
This is an observational study that looks back at medical and pharmacy records of women with atopic dermatitis around pregnancy. It may help researchers better understand how this condition affects pregnant patients and pregnancy-related care.
Boston, MassachusettsAges 18–49 - NCT04380038RecruitingPhase 4
Viral infection study in well-controlled asthma adults
This study looks at how a viral infection affects people with well-controlled asthma. It tests whether specific asthma-related immune signals can predict who reacts more to a virus, which may help guide future asthma care.
Charlottesville, VirginiaAges 18–40 - NCT05790330Recruiting
Study brain–skin links in teenagers with eczema
This study looks at how eczema may be connected to the brain and sleep, using questionnaires and MRI scans. It may help researchers understand what drives symptoms and how treatments could be improved.
LondonAges 12–18 - NCT06039241Recruiting
Long-term Dupilumab treatment for atopic dermatitis
This study looks at how well Dupilumab works over time for people with atopic dermatitis (eczema). It includes adults, teens, and children ages 6 and up.
AachenAges 6 years+ - NCT06182436Recruiting
Virtual reality for pain during eczema injection
This trial tests whether playing a virtual reality game during a dupilumab injection (for eczema) can help reduce pain and anxiety. It's for kids and teens aged 6 to 17 who are already taking or about to start this medicine.
Montreal, QuebecAges 6–17 - NCT06226610RecruitingPhase 2
Testing dupilumab for severe itching after burn injuries
This trial tests if dupilumab (Dupixent) can help adults with long-lasting, severe itching from healed burn scars. It is for people whose itching has not improved with standard treatments like antihistamines.
Akron, OhioAges 18–60 - NCT06385236RecruitingPhase 4
Asthma genetics study to find better treatments
This study looks at how your genes affect your asthma medications. It tests if knowing your DNA can help predict which treatment works best for you and why.
Scottsdale, ArizonaAges 18–75 - NCT06501807Recruiting
Biologics for severe nasal polyps: a French registry study
This study follows patients in France who are receiving biologic treatments for severe nasal polyps with chronic sinusitis. It collects information on how well these treatments work and their side effects over time.
LilleAges 18 years+
Common questions
- Are there clinical trials studying Dupilumab?
- Yes. Clin2 currently lists 55 recruiting studies that include Dupilumab, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Dupilumab trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Dupilumab an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Dupilumab or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.