Ketamine after cardiac arrest to protect the brain
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your cardiac arrest was outside the hospital, likely caused by a heart problem, and your first recorded heart rhythm was shockable (like ventricular fibrillation)
- Your average blood pressure was above 40 mmHg (a measure of how hard your heart is pumping)
- The emergency team decided to place a breathing tube before arriving at the hospital
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a small dose of epinephrine (a medicine that helps restart the heart) given early during a cardiac arrest outside the hospital can improve brain function and survival. It is for adults whose heart stopped due to a medical reason and who receive advanced life support from emergency teams.
This study tests a treatment approach aimed at protecting the brain and supporting better blood flow to the brain after a cardiac arrest. It may help some people who are in a coma right after the event recover more safely or with less brain injury.
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
This Phase 3 trial studies treatments given after a person survives an out-of-hospital cardiac arrest to improve recovery and survival. It is for patients who stay unconscious for a short time after circulation returns, and who meet safety conditions.
This trial studies whether ketamine given soon after an ischemic stroke (blocked blood flow) can reduce early brain injury. It may help some people by limiting harmful brain reactions after stroke.
This trial studies whether ketamine can improve outcomes for adults with severe traumatic brain injury when they are in the ICU and need sedation. It focuses on patients who have pressure monitoring inside the brain soon after admission.
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