Ketamine after cardiac arrest to protect the brain
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your cardiac arrest was outside the hospital, likely caused by a heart problem, and your first recorded heart rhythm was shockable (like ventricular fibrillation)
- Your average blood pressure was above 40 mmHg (a measure of how hard your heart is pumping)
- The emergency team decided to place a breathing tube before arriving at the hospital
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a low dose of epinephrine (a medicine that helps restart the heart) during a cardiac arrest can improve brain recovery. It compares standard treatment with adding this low dose to see if more patients recover without brain damage.
This study tests a treatment approach aimed at protecting the brain and supporting better blood flow to the brain after a cardiac arrest. It may help some people who are in a coma right after the event recover more safely or with less brain injury.
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
This Phase 3 trial studies treatments given after a person survives an out-of-hospital cardiac arrest to improve recovery and survival. It is for patients who stay unconscious for a short time after circulation returns, and who meet safety conditions.
This trial tests whether a single dose of ketamine, given within 24 hours of a stroke, can reduce brain damage and improve recovery. It is designed for people who had a recent ischemic stroke and who are not eligible for standard clot-busting or clot-removal treatments.
This study tests whether giving ketamine during heart surgery helps protect the brain in young children. It is for children aged 1 month to 5 years who are having surgery to fix a hole in the wall between the heart chambers (atrial or ventricular septal defect).
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