Treatment
Nirogacestat clinical trials
We’re tracking 5 recruiting studies that include Nirogacestat, each written for real people, not researchers, below.
Recruiting studies
- NCT07176689RecruitingPhase 4
Nirogacestat for desmoid tumors in premenopausal women
This trial tests a drug called nirogacestat to see if it can help premenopausal women with desmoid tumors (a type of non-cancerous growth) that are causing symptoms or getting worse. It aims to offer a new treatment option for those who need systemic therapy.
BrusselsAges 18–40 - NCT05573802RecruitingPhase 1/Phase 2
Belantamab and other medicines for new multiple myeloma
This early-phase study tests how safe and effective belantamab mafodotin is when combined with lenalidomide and dexamethasone, plus a medicine called nirogacestat, in people with newly diagnosed multiple myeloma who cannot have stem cell transplant. It may help shrink the cancer and improve outcomes, while doctors track side effects.
AthensAges 18 years+ - NCT05879146RecruitingPhase 2
Nirogacestat for desmoid tumors with tumor growth monitoring
This Phase 2 study tests nirogacestat (a targeted medicine) in people with desmoid tumors that are growing. It also studies how tumors respond—or don’t respond—by using repeated tumor scans and sometimes repeated tumor biopsies.
Houston, TexasAges 18 years+ - NCT05949099RecruitingPhase 2
Cryoablation plus nirogacestat for progressing desmoid tumors
This Phase 2 study tests whether combining cryoablation (freezing the tumor) with nirogacestat (a targeted pill treatment) can better control desmoid tumors that are growing or causing symptoms. It may help shrink tumors and improve symptoms, especially when freezing alone is challenging.
Palo Alto, CaliforniaAges 18 years+ - NCT05137054RecruitingPhase 1
Linvoseltamab combo for hard-to-treat multiple myeloma
This trial tests a new drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has stopped responding to standard therapies. It may be an option if you have already tried several treatments and are looking for a new approach.
La Jolla, CaliforniaAges 18 years+
What Nirogacestat is being studied for
Conditions with recruiting Nirogacestat studies.
Common questions
- Are there clinical trials studying Nirogacestat?
- Yes. Clin2 currently lists 5 recruiting studies that include Nirogacestat, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Nirogacestat trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Nirogacestat an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Nirogacestat or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.