Clinical trials
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) clinical trials
Below are recruiting chronic rhinosinusitis with nasal polyps (crswnp) clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07520162RecruitingPhase 3
Tezepelumab for Nasal Polyps in Chinese Adults
This study tests whether tezepelumab, a new injectable medicine, can help reduce nasal polyps and improve symptoms like nasal congestion, loss of smell, and sleep problems. You would receive the study drug while continuing your current nasal steroid spray, and your doctors would track how your symptoms change.
BeijingAges 18 years+ - NCT07399665Recruiting
Tezepelumab for chronic sinusitis with nasal polyps in Russia
This study tracks how well tezepelumab works for people with chronic sinusitis and nasal polyps in real-world settings. It aims to see if this medication reduces symptoms and the need for surgery.
Kazan'Ages 18 years+ - NCT06683261Recruiting
Real-world study of biologics for nasal polyps
This study follows people with chronic rhinosinusitis and nasal polyps who are starting a biologic medication (omalizumab, mepolizumab, or dupilumab) to see how well it works in real life.
AalstAges 18 years+ - NCT05246267Recruiting
Dupilumab study for chronic sinus disease with nasal polyps
This study looks at how dupilumab (an injection medicine) helps people with chronic rhinosinusitis with nasal polyps, including how well it works across different ethnic backgrounds. You may be able to join if you’ve been diagnosed and you can get dupilumab through insurance or a patient assistance program.
The Bronx, New YorkAges 18–99 - NCT07286201Enrolling by invitation
Nasal packing with steroid to improve sinus surgery results
This study tests a special nose dressing that slowly releases a steroid to reduce inflammation and improve healing after sinus surgery for chronic sinusitis with or without nasal polyps.
Colorado Springs, ColoradoAges 18 years+ - NCT06398873Recruiting
Dupilumab and nasal lining in chronic sinusitis with polyps
This study tests whether dupilumab, a medication given as an injection, helps improve the lining of the nose in people with chronic sinus inflammation and nasal polyps. If you have nasal polyps and are about to start dupilumab, or if you have sinusitis without polyps, you may be eligible to join.
Vienna, AustriaAges 18–99 - NCT07125586Recruiting
Light-based test for eosinophilic nasal polyps during surgery
This study tests a new tool that uses light (spectroscopy) to instantly detect a type of nasal polyp during surgery. The goal is to help doctors identify polyps that are driven by eosinophils, which may guide better treatment choices for you.
Qingdao, ShandongAges 18–65 - NCT07107256RecruitingPhase 3
Study of TQC2731 for chronic sinusitis with nasal polyps
This trial tests an injectable drug called TQC2731 for people with chronic sinusitis and nasal polyps that haven't been controlled well enough by standard treatments like steroid sprays or surgery. The goal is to see if it helps reduce nasal congestion, improve sense of smell, and shrink polyps.
Fuyang, AnhuiAges 18–75 - NCT07633158Recruiting
Real-world study of tezepelumab for chronic nasal polyps
This study follows patients with chronic rhinosinusitis with nasal polyps (CRSwNP)—a condition causing blocked sinuses and nasal growths—who are starting a new biologic medication called tezepelumab. Researchers will track how symptoms and quality of life improve over time in everyday medical practice.
HamburgAges 18–130 - NCT07132827RecruitingPhase 3
Study of SHR-1905 for chronic sinusitis with nasal polyps
This trial tests a new injection (SHR-1905) for people with chronic sinusitis and nasal polyps who still have symptoms despite using standard nasal spray treatments. It aims to see if the drug can reduce polyp size and improve symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07498374Recruiting
Drug-eluting stent for eosinophilic sinusitis with nasal polyps
This trial tests a fully dissolvable stent that releases medication inside the sinuses after surgery. It is for patients with a specific type of sinusitis (eosinophilic) and nasal polyps who either need surgery or have had surgery and show early signs of inflammation returning.
Xi'an, ShaanxiAges 18–65 - NCT07446738Recruiting
Study of recovery and quality of life after nasal polyp surgery
This study looks at how well patients recover and their quality of life after surgery for nasal polyps caused by chronic sinusitis. It is for people in China who have just had surgery to remove nasal polyps.
ChangchunAges Any age - NCT06776042Recruiting
Nasal polyps and smell loss study
This study looks at why people with nasal polyps lose their sense of smell and how it might come back. You may be able to join if you have had nasal blockage, runny nose, smell loss, or facial pain for at least 12 weeks, have polyps seen inside your nose, and are using a steroid spray regularly.
BrusselsAges 18–70 - NCT06338995RecruitingPhase 3
Lebrikizumab for nasal polyps and sinusitis
This trial tests a new injectable medicine (lebrikizumab) for people with chronic sinusitis and nasal polyps that steroid treatments haven't controlled. It aims to reduce polyp size and improve breathing, smell, and congestion.
Birmingham, AlabamaAges 12 years+ - NCT05938972Recruiting
Study of biologic medicines in severe CRSwNP patients
This study looks at how “biologic” medicines work in real-life care for people with severe chronic rhinosinusitis with nasal polyps (CRSwNP). It may help confirm which patients benefit and how treatment is used in everyday practice.
GhentAges 18–80 - NCT07436949RecruitingPhase 1/Phase 2
Study of BBT002 for chronic sinusitis with nasal polyps and asthma
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06914908Enrolling by invitationPhase 2
Long-term safety study of lunsekimig for nasal polyps
This study tests the long-term safety and effectiveness of a medication called lunsekimig for people with chronic sinusitis and nasal polyps. It is for those who already completed a previous study on this drug.
La Jolla, CaliforniaAges 18 years+ - NCT07187583RecruitingPhase 4
Reducing biologic doses for chronic sinusitis with polyps
This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.
AalborgAges 18 years+ - NCT06118554Recruiting
Testing a 3D-printed tool for better sinus rinses
This study tests whether a 3D-printed tool can help people with chronic sinusitis get better results from nasal rinses. It might help if your sinus rinses don't reach deep enough into your nasal passages.
Columbus, OhioAges 18–75 - NCT07134686Recruiting
Combined lung and ear-nose-throat care for asthma and sinusitis
This trial tests if seeing a lung specialist and an ear-nose-throat doctor together in one visit helps people with asthma and chronic sinusitis (with nasal polyps) feel better than seeing each specialist separately. You may qualify if your asthma or sinusitis is not well-controlled and you've used steroid pills in the past year.
MarseilleAges 18 years+ - NCT06824649RecruitingPhase 4
Comparing biologics for chronic sinusitis with nasal polyps
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
Portland, OregonAges 18 years+ - NCT05009758Recruiting
Asthma and nasal polyps study to match immune patterns
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
ViennaAges 18–99 - NCT05902325RecruitingPhase 4
Testing who benefits most from mepolizumab for nasal polyps
This study looks at why some people with severe chronic nasal polyps respond better to mepolizumab. It may help doctors predict who will benefit from the medicine, and who may need a different plan.
Montreal, QuebecAges 18 years+ - NCT06129552Recruiting
Healthy nose cells study for sinusitis insight
This study is looking at healthy people to understand how certain cells in the nose work. It will compare them to people with sinus problems to learn what goes wrong in chronic sinusitis with nasal polyps.
LeuvenAges 18 years+
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Common questions
- Are there clinical trials for chronic rhinosinusitis with nasal polyps (crswnp)?
- Yes. Clin2 currently lists 29 recruiting chronic rhinosinusitis with nasal polyps (crswnp) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic rhinosinusitis with nasal polyps (crswnp) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic rhinosinusitis with nasal polyps (crswnp) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.