Understanding genetics of insulin resistance and diabetes
Part of Hormones & metabolism clinical trials.
This research study looks at the genes and immune system factors that cause severe insulin resistance—a condition where the body doesn't respond well to insulin. Researchers want to understand why some people develop this problem and study family members and healthy volunteers to learn more.
Summary written for real people, not researchers, by Clin2.
Who can take part
- At least 6 months old (for patients with insulin resistance or family members); at least 12 years old for healthy volunteers
- If you have severe insulin resistance: very high fasting insulin levels, need large amounts of insulin daily, or show certain physical signs like dark skin patches or abnormal fat distribution
- If you're a family member of someone in the study: you must be a biological relative of a patient with suspected genetic insulin resistance
- Able to understand the study and sign consent (parent or guardian can sign for minors)
- For healthy volunteers: no active medical conditions and not currently taking most prescription or non-prescription medications
- For pregnant women: family members cannot participate if pregnant at enrollment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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