Clin2
NCT06478121Possibly a fitRecruiting

Understanding how genes affect beta cells

Diabetes MellitusMonogenic DiabetesHyperinsulinism

Part of Hormones & metabolism clinical trials.

This study looks at how specific genetic changes affect beta cells, which make insulin. It may help people with rare genetic forms of diabetes or other beta cell disorders, and also needs healthy volunteers for comparison.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
6 years to 99 years
Study type
Observational

Who can take part

  • You must be able to understand the study and agree to take part.
  • You can be of any sex, ethnicity, or from any country.
  • You may have a known genetic variant that affects beta cell function (the cells that make insulin), or you may be a healthy volunteer without that variant.
  • If you are a healthy volunteer, you will be matched by age, sex, and BMI to someone with the variant.
  • Your age must be between 6 and 99 years old.
  • If you need an MRI scan, you cannot have any metal implants or devices in your body, nor be very claustrophobic.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07621445Recruiting
Understanding Genetic Risk in Recently Diagnosed Diabetes

This study looks at genetic factors in people recently diagnosed with diabetes to understand what might predict who needs insulin treatment. Researchers will analyze blood samples and medical information to see if genetic testing could help doctors predict your treatment path.

Changsha, Hunan
NCT06746610Recruiting
Personalized management for inherited diabetes in young adults

This study looks for people with a type of diabetes that runs in families, often diagnosed at a young age. It uses genetic testing to find the exact cause and then tailor treatment to each person.

Tianjin
NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis

This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.

Aurora, Colorado
NCT03648918Recruiting
Study family genetics in type 1 diabetes

This study looks at genetic patterns in families where someone has type 1 diabetes (an autoimmune condition). It may help researchers understand why type 1 diabetes happens and who is at risk.

Milwaukee, Wisconsin
NCT07564518Not yet recruiting
Glucose monitoring in people with varying blood sugar patterns

This study uses a continuous glucose monitor to track blood sugar fluctuations in people with different types of glucose metabolism issues, including those with genetic diabetes or high insulin levels. The goal is to understand how blood sugar varies, which may help improve care.

NCT07780513Recruiting
Genetics of muscle insulin resistance study

This study looks at how genes affect the way muscles use sugar, which can help understand insulin resistance. Participants will have tests and procedures, including a glucose drink test and a muscle biopsy, to see how their bodies handle sugar.

San Antonio, Texas

Hear when a new Diabetes Mellitus trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.