Understanding Genetic Causes of Immune System Disorders
Part of Genetic & congenital, Hormones & metabolism, Immune system & allergy clinical trials.
This research study investigates why some people have weak or poorly functioning immune systems. By studying you and your relatives, researchers hope to identify genetic factors that cause these conditions and eventually develop better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have reduced numbers of certain immune cells (T cells, B cells, or NK cells) OR normal numbers but these cells don't work properly
- You are at least 6 months old (if you're a patient or sibling) or at least 18 years old (if you're another biological relative like a parent or grandparent)
- You do not have a previously diagnosed genetic immune condition
- If you are an adult, you must be able to understand and consent to the study
- You are not currently pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study aims to better understand primary immune disorders by collecting genetic and blood (and related) information. It may help researchers identify what causes these conditions and improve future testing and care.
This study looks for genetic causes of immune problems, such as unusually frequent infections, abnormal allergies, or autoimmune or inflammation conditions. It may help by improving how doctors understand these disorders and by matching families with possible genetic diagnoses.
This research study investigates problems with immune system cells called phagocytes that help fight infections. Researchers will study patients with suspected immune defects and their blood relatives to better understand these conditions and develop better care.
This study screens people who may have an inherited immune system condition (like problems with immune cell growth or death) and their blood relatives. The goal is to understand the condition better by collecting blood samples for testing.
This study looks at how the immune system works in people who have abnormal immune function, often shown by unusual or repeated infections or long-lasting inflammation. It may involve tests using blood samples and storage of blood for future research.
This research looks at how inherited (genetic) changes may affect the immune system in people with immune problems. It may help by improving understanding of these conditions and, in some cases, guiding faster care for a baby after birth.
Hear when a new Severe Combined Immunodeficiency trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.