Study immune system problems in people with unusual infections
Part of Blood & lymphatic, Genetic & congenital, Immune system & allergy, Infections, Lungs & breathing clinical trials.
This study looks at how the immune system works in people who have abnormal immune function, often shown by unusual or repeated infections or long-lasting inflammation. It may involve tests using blood samples and storage of blood for future research.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your child) should have a history of unusual, repeated, or long-lasting infections or inflammation, or past abnormal immune test results
- You must be able to see the NIH Clinical Center as required: at least age 2 for outpatient visits, with no active infection at the visit
- You should have a primary doctor outside of NIH
- You must be willing to have blood taken and have it stored for future studies
- If you are being screened as a healthy volunteer, you must be age 18 to 85 and have no major health conditions like HIV, hepatitis, or serious heart/lung/kidney disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition where the immune system cannot fight certain infections. The treatment uses your own blood stem cells, which are modified in the lab to help your body produce working immune cells.
This study is checking levels of antibodies and immune-signaling molecules (cytokines) in people with chronic granulomatous disease (CGD). It aims to better understand the immune system in CGD, which may help with future treatments.
This study looks at immune system differences that can make some people get unusual or frequent fungal (fungus) infections. It may help researchers better understand these conditions, and you may be asked to store blood for future research.
This study looks for genetic causes of immune problems, such as unusually frequent infections, abnormal allergies, or autoimmune or inflammation conditions. It may help by improving how doctors understand these disorders and by matching families with possible genetic diagnoses.
This study screens people who may have an inherited immune system condition (like problems with immune cell growth or death) and their blood relatives. The goal is to understand the condition better by collecting blood samples for testing.
This study looks at how the immune system works in people who have—or might have—an increased risk of infections. It also enrolls their healthy blood relatives so researchers can compare immune features; results may help doctors understand who is at higher risk and why.
Hear when a new Chronic Granulomatous Disease (CGD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.