Study of how Sjogren’s disease starts and changes over time
Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be able to sign an informed consent form
- Be at least 16 years old
- Have Sjogren’s disease based on study classification rules (or be close enough to qualify as “incomplete”)
- Be able and willing to come back for follow-up visits as required
- Not have another medical or mental health issue that could better explain your symptoms or affect the study
- Not be a NIH employee who works directly with the lead researcher, or a close relative/co-worker of the lead researcher
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at diseases that involve the salivary (saliva) glands, and may also include people with active hepatitis, oral cancer, or healthy adults. Researchers collect blood, urine, saliva, and sometimes tissue to better understand what’s happening and how these conditions relate to saliva and oral health.
This study follows people who may have Sjögren’s disease to better understand how to diagnose it. If you have symptoms like dry eyes or dry mouth, this could help researchers confirm the diagnosis and learn what tests best explain it.
This study compares saliva, dental plaque, and stool samples from people with Sjogren's syndrome and healthy controls to understand how the mouth and gut bacteria differ. Participation is simple and involves providing samples during a dental visit and at home.
This study tests an experimental treatment made from a person's own blood cells, called HuMoSCs, to see if it can help reduce dryness and other symptoms of Sjogren's syndrome. It is for people who have symptoms of the condition but have not yet been officially diagnosed.
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
This study follows adults with primary Sjögren’s syndrome. It may help researchers understand the condition better by using information from people who have already joined the earlier ASSESS study.
Hear when a new Sjogren's Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.