Saliva and stool sampling for Sjogren's syndrome study
Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This study compares saliva, dental plaque, and stool samples from people with Sjogren's syndrome and healthy controls to understand how the mouth and gut bacteria differ. Participation is simple and involves providing samples during a dental visit and at home.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are either a healthy adult or an adult diagnosed with Sjogren's syndrome according to specific criteria
- Willing to provide saliva and a dental plaque sample from your deepest gum pocket
- Willing to collect a stool sample at home and, if in the Sjogren's group, swallow a small capsule to sample your gut
- No need for antibiotics before dental cleanings (certain heart conditions or joint replacements may exclude you)
- No active mouth sores or infections, and no history of salivary gland disorders (like sarcoidosis or prior radiation to head/neck)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at diseases that involve the salivary (saliva) glands, and may also include people with active hepatitis, oral cancer, or healthy adults. Researchers collect blood, urine, saliva, and sometimes tissue to better understand what’s happening and how these conditions relate to saliva and oral health.
This study follows people who may have Sjögren’s disease to better understand how to diagnose it. If you have symptoms like dry eyes or dry mouth, this could help researchers confirm the diagnosis and learn what tests best explain it.
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
This study tests the safety of a daily pill called Tofacitinib for adults with mild-to-moderate Sjögren's disease. It aims to see if this drug helps manage symptoms when other treatments haven't worked well.
This Phase 1 trial tests an experimental probiotic called R-2487 for people with Sjogren's syndrome. The goal is to see if it is safe and might help with symptoms like dry eyes and dry mouth.
This study tests an experimental treatment made from a person's own blood cells, called HuMoSCs, to see if it can help reduce dryness and other symptoms of Sjogren's syndrome. It is for people who have symptoms of the condition but have not yet been officially diagnosed.
Hear when a new Sjogren's Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.