Bupropion for teens with major depression
Part of Mental health clinical trials.
This study tests whether bupropion helps children and teens with major depressive disorder (MDD) and checks its safety. You may be able to join if your depression symptoms fit specific scoring and timing rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your age is 7 up to (but not including) 18 at the first screening visit
- A parent/legal guardian can consent and the child can assent to joining the study
- A clinician confirms you have major depressive disorder (MDD) at screening and baseline visits
- Your current depressive episode has lasted at least 4 weeks
- Your symptom rating scores are high enough (CDRS-R) and your overall severity is moderate to severe (CGI-S)
- You can swallow study medicine, and you have no history of seizures or serious injury to the head
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a new drug called AXS-05 can prevent depression from coming back, compared to an older drug called bupropion. If you have major depression and are at risk of relapse, this trial may help you stay well.
This study tests a new way of choosing antidepressants for people with major depression. It's designed for adults aged 19–65 who have moderate to severe depression and are either starting a new antidepressant or have been off psychiatric meds for at least a month.
This study tests an investigational drug called BMS-986511 in adults with moderate to severe depression. The goal is to see if it can improve symptoms.
This trial tests whether vortioxetine helps reduce symptoms of major depression in Japanese teenagers aged 12-17. It compares the study drug to a placebo to see if it is safe and effective.
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
This study tests a new type of brain stimulation called accelerated intermittent theta burst stimulation (aiTBS) in young people (ages 13-20) with depression who have not tried many treatments before. The goal is to see if this treatment can safely help reduce depression symptoms.
Hear when a new Major Depressive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.