Clin2
NCT02133196Possibly a fitRecruiting

T-cell treatment for lung cancer that has spread

Advanced Non-Small Cell Lung CancerSquamous Cell CarcinomaAdvanced NSCLCAdenosquamous CarcinomaAdenocarcinoma

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This Phase 2 study tests a T-cell–based immunotherapy for people with metastatic non-small cell lung cancer that has grown despite prior treatment. It may help your immune system recognize and fight your cancer using cells made from your tumor.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
85 people
Ages
18 years to 72 years
Study type
Interventional

Who can take part

  • You have non-small cell lung cancer that has spread (stage IV) or cannot be removed, and you’re not eligible for neuroendocrine tumors
  • You have at least one tumor spot that can be surgically removed so the study can grow tumor-fighting T cells (TILs)
  • Your cancer has already been treated with at least one initial (first-line) systemic therapy, and it has gotten worse
  • Brain metastases are allowed only if there are 3 or fewer, they’re under 1 cm, and they’re not causing symptoms; treated spots must be stable
  • You must have a generally good body status (ECOG 0 or 1) and be age 18 to 72
  • You need to meet immune and blood/organ lab thresholds and be free of HIV and active hepatitis infections

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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