Test a nerve-blocking medicine in kidney disease
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 1 study tests whether a medicine that reduces nerve signals (“sympatholysis”) is safe and how it affects people with chronic kidney disease. It may help researchers understand new ways to protect the kidneys, but the main goal here is safety.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 75 years old
- You have kidney problems (Stages III or IV) OR you are a kidney transplant recipient
- You usually exercise less than 20 minutes, twice per week
- You must be able to follow study instructions and cooperate
- You must be able to exercise on a stationary bicycle
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests how the body’s blood-pressure control responds to exercise in people with chronic kidney disease (and some transplant recipients), compared with people without kidney disease. It may help researchers learn safer ways to exercise and manage blood pressure for people with kidney disease.
This study tests a device that gently stimulates a nerve in your ear to see if it can help people with chronic kidney disease (CKD). The device is non-invasive and may improve how your body handles kidney-related issues.
This study tests a single dose of an investigational medicine (NNC0537-1482) to see how it moves through the body in people with different levels of kidney function. It may help researchers understand how the drug is processed so it can be dosed safely in future studies.
This Phase 2 study tests how engaging in supervised exercise affects the body’s blood-vessel responses in people with chronic kidney disease (CKD) who don’t exercise regularly. It may help researchers understand whether exercise could be beneficial for CKD-related health changes.
This study tests a new treatment that uses a device to calm overactive nerves in the kidneys, which may help lower high blood pressure. It is for people who are already taking at least two blood pressure medications and still have high readings.
This trial tests whether a mindfulness-based program can help people living with moderate-to-advanced kidney disease. It may improve how you feel day-to-day and how you manage symptoms, while researchers track kidney-related health and safety.
Hear when a new Chronic kidney disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.