Clinical trials
Chronic kidney disease clinical trials
A gradual loss of kidney function over time. We’re tracking 572 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Fairhope, AlabamaAges 18 years+ - NCT03573089Recruiting
Testing higher vs standard phosphate targets in dialysis patients
This trial compares two treatment goals for blood phosphate levels in people with end-stage kidney disease who are on dialysis. It may help determine which target is safer and works better in real-world care.
Camperdown, New South WalesAges 18 years+ - NCT07380113RecruitingPhase 4
Comparing two drugs for sleep in dialysis patients with itch
This trial tests if anrikefon or nalfurafine improves sleep quality in people on hemodialysis who have chronic kidney disease-related itching. It aims to find a better treatment for both itch and sleep problems.
Guangzhou, GuangdongAges 18–75 - NCT07781124Recruiting
Remote monitoring for kidney dialysis patients
This study compares the effectiveness and resource use of remote patient monitoring across different dialysis methods for people with end-stage renal disease. It aims to see if remote monitoring can improve care and outcomes.
Beijing, Beijing MunicipalityAges 18–79 - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT07107945RecruitingPhase 3
Study of empagliflozin for children with chronic kidney disease
This trial tests if empagliflozin, a daily pill, is safe and helps children ages 2–17 with chronic kidney disease (CKD). Your child may be eligible if they have reduced kidney function and elevated protein in their urine, and are already on stable kidney treatments.
Birmingham, AlabamaAges 2–17 - NCT05457283RecruitingPhase 3
Finerenone safety study for children with kidney disease
This trial studies how safely finerenone works over 18 months in children and young adults with chronic kidney disease who also take an ACE inhibitor or ARB. It aims to better understand long-term side effects when used together with standard kidney blood-pressure medicines.
Palo Alto, CaliforniaAges 1–18 - NCT07592000RecruitingPhase 1/Phase 2
New Treatment for Type 1 Diabetes With Kidney Disease
This study tests a new experimental medication for people with type 1 diabetes who experience dangerous low blood sugar episodes and have early-stage kidney disease. The trial aims to help improve blood sugar control and reduce these risky episodes.
Miami, FloridaAges 18–70 - NCT06430684RecruitingEarly Phase 1
SGLT2 inhibitor trial for children with kidney disease
This trial tests a medication called SGLT2 inhibitor (a type of diabetes drug that may also help protect the kidneys) in children with chronic kidney disease. It aims to see if the drug is safe and easy to use in children ages 2–18 with moderate to severe kidney problems.
Chicago, IllinoisAges 12–25 - NCT07768865Recruiting
Artery stiffness in young people with kidney disease
This study looks at how stiff the arteries are in children and young adults with chronic kidney disease (CKD) compared to healthy controls. The results may help doctors better understand heart risks and improve care for young people with kidney problems.
London, Greater LondonAges 10–25 - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100 - NCT07348237RecruitingPhase 1
Testing a new kidney disease drug in patients with kidney failure
This trial tests the safety of a new medicine (MK-2828) in people with advanced kidney disease or on dialysis, and compares them to healthy volunteers. The goal is to understand how the drug works in the body and if it's safe for these patients.
Miami Lakes, FloridaAges 24–85 - NCT05846581Recruiting
Dialysis graft registry for adults getting a new vascular graft
This registry follows adults with kidney failure who need a dialysis access connection in the arm using the GORE ACUSEAL graft. It helps track outcomes and safety over time while you receive standard dialysis care.
BielefeldAges 18 years+ - NCT04802395Recruiting
KidneyIntelX check for people with diabetes and early kidney disease
This study looks at how well a kidney test tool called KidneyIntelX works in real-world care for people with type 2 diabetes and certain stages of kidney disease. It may help doctors use the tool to better understand kidney risk and guide next steps.
New York, New YorkAges 23 years+ - NCT07105670Recruiting
Replacing high-protein foods in chronic kidney disease
This study looks at how replacing high-protein foods affects people with chronic kidney disease. If you join, you will eat a carefully controlled diet to help researchers understand if changing your protein intake can improve your kidney health.
West Lafayette, IndianaAges 40–70 - NCT07754097Recruiting
Tracking your health at home for chronic kidney disease
This study tests if regularly tracking your blood pressure, diet, and medications through a mobile app can help monitor kidney disease progression. It aims to see if this self-management approach helps you stay healthier.
Daejeon, DJAges 19–84 - NCT07748858Recruiting
Heart care support for older African American patients
This study aims to improve care for older African American patients with heart conditions and other health problems. It tests ways to provide more patient-centered support.
Birmingham, AlabamaAges 50–99 - NCT07241390RecruitingPhase 3
Study of orforglipron for heart and kidney health.
This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.
Bahía BlancaAges 50 years+ - NCT06026436Recruiting
Predicting clot and bleeding risk in kidney disease patients after a heart attack
This trial tests whether a blood test looking at platelets and tiny cell particles can help predict future blood clots or bleeding in people who have both chronic kidney disease and a recent heart attack. The goal is to improve treatment safety.
MarseilleAges 18–90 - NCT05071131Recruiting
Inulin supplement to improve gut health in kidney disease
This trial studies whether taking inulin—a dietary fiber—can improve gut bacteria and the gut barrier in people with end-stage kidney disease on hemodialysis. It may help reduce gut-related problems that can affect overall health in kidney disease.
BerlinAges 18–75 - NCT04397159Recruiting
Exercise program to reduce tiredness in some kidney patients
This trial studies whether doing a combination exercise program can reduce “fatigability,” meaning feeling unusually tired or weak during activity, in Veterans with moderate-to-advanced chronic kidney disease. It also compares results with people without kidney disease and checks for safety, especially for heart and joint health.
Washington D.C., District of ColumbiaAges 50–85 - NCT04721652Recruiting
Track drinking and recovery after hemodialysis sessions
This study looks at how fluid intake after each hemodialysis treatment affects your health. It may help find safer, easier guidance on how much to drink between treatments.
London, OntarioAges 18 years+ - NCT06466785RecruitingPhase 3
Study of Efepoetin Alfa for anemia in kidney dialysis patients
This study tests a new drug called Efepoetin Alfa to treat anemia in people with chronic kidney disease who are on dialysis. The goal is to see if it can safely raise red blood cell levels and reduce the need for other anemia treatments.
YerevanAges 18 years+ - NCT07666815RecruitingPhase 1/Phase 2
Exercise and creatine during dialysis for kidney disease
This trial tests if doing exercise while on dialysis and taking creatine can help people with chronic kidney disease. It aims to find a safe and effective way to improve health during treatment.
Colima, ColiimaAges 18 years+
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Chronic kidney disease trials by city
Studies with a site in or near these metro areas.
Chronic kidney disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for chronic kidney disease?
- Yes. Clin2 currently lists 572 recruiting chronic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.