Reducing Immunosuppression in Older Kidney Transplant Patients (RIOT Trial)
Part of Immune system & allergy, Kidney & urinary clinical trials.
This trial tests whether older kidney transplant recipients can safely reduce their immunosuppression medications using a special monitoring tool called Trugraf. If you are over 55, have had a stable transplant, and want to possibly lower your medications, this study may be for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 55 years old or older and have had only one kidney transplant (or two if the first was from a living donor).
- You do not have HIV.
- You are currently taking tacrolimus along with either mycophenolate mofetil or Myfortic (a type of mycophenolate).
- You have not had any rejection episodes since your transplant, and a recent biopsy (if done) shows no signs of rejection.
- Your blood tests show no antibodies that are strong enough to cause rejection (DSA and cPRA below certain levels).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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