Study angiotensin medicine to improve metabolism in obesity
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 to 60 years old
- Body mass index (BMI) between 30 and 40 (obesity, not “morbid obesity” over 40)
- Have insulin resistance (a lab measure called HOMA2-IR higher than 2.2)
- Have high blood pressure (repeated readings above 130/85 or you take blood pressure medicine)
- Cannot be pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
This study tests whether a natural protein called angiotensin-(1-7) can improve heart health in people with obesity and high blood pressure. It may help researchers find new ways to treat these conditions together.
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
This study looks at how the body adapts in people with different body weights and insulin sensitivity. It compares lean adults and those with obesity, with or without insulin resistance, to understand metabolism better. Participation involves a few visits and some tests.
This study checks how reliable routine lab tests and research techniques are for metabolism research. It may help you if you are a healthy adult with a stable weight and no major health conditions.
This trial tests whether a simple metabolic test (using your blood or urine) can help your doctor personalise which blood pressure medicine is best for you. The goal is to improve blood pressure control with fewer side effects.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.