CAR T therapy using blood immune cells for CD70 cancers
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This trial tests a personalized immune-cell treatment (CAR T) built from your own blood lymphocytes. It targets cancers that show a marker called CD70, aiming to slow or stop the cancer when other treatments didn’t work.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your cancer must test positive for CD70 on tumor tissue (a lab must confirm the result).
- Your cancer must be unresectable (can’t be fully removed by surgery); for Phase II it must also be measurable on scans.
- You must be an adult (18–72) and able to do daily activities fairly well (ECOG 0 or 1).
- You must have had at least one prior standard cancer treatment (or your cancer came back or didn’t respond).
- You may have up to 3 small, non-symptomatic brain metastases (and any treated ones must be stable after radiation).
- You must meet key blood and organ health requirements (immune, liver/kidney, and blood counts) and be well enough to consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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