Autologous mitochondria treatment for critically ill heart children on ECMO
Part of Heart & circulation clinical trials.
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be under 18 years old
- Be on ECMO (a machine that supports heart and lungs)
- Be cared for in the Cardiac Intensive Care Unit for a heart issue
- Doctors have concerns about reduced blood flow injury (ischemic injury)
- Not have a known mitochondria disorder
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
This trial is testing a new device (MiniLung Petite Kit) for babies and young children with severe lung or heart failure. The device helps oxygenate the blood and remove carbon dioxide, giving the lungs and heart a chance to rest and heal.
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
This study looks at how well antibiotics and other anti-infective drugs work in very sick patients who are on a heart-lung machine called ECMO. If you're in the ICU with a serious infection, this trial could help doctors figure out the best dose for you.
This study uses a portable MRI to look for brain injuries in children on ECMO (a heart-lung support machine). It may help doctors detect problems early and improve care.
Hear when a new Extracorporeal Membrane Oxygenation Complication trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.