Clinical trials
Extracorporeal Membrane Oxygenation Complication clinical trials
Below are recruiting extracorporeal membrane oxygenation complication clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05163925Recruiting
Study of a heart-lung device for emergency life support
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
ViennaAges 18 years+ - NCT06469801Recruiting
Portable MRI for brain injury in children on ECMO
This study uses a portable MRI to look for brain injuries in children on ECMO (a heart-lung support machine). It may help doctors detect problems early and improve care.
Kansas City, MissouriAges birth–17 years - NCT06276010Recruiting
Nafamostat mesilate for blood thinning in ECMO patients
This trial tests a medicine called nafamostat mesilate to prevent blood clots in patients who need ECMO (a machine that helps your heart and lungs) after heart surgery. It may offer a safer way to thin the blood compared to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05959252RecruitingPhase 2
Bivalirudin vs heparin for blood thinning during ECMO
This Phase 2 trial compares two blood-thinning medicines—bivalirudin and heparin—in people on ECMO (a machine that supports breathing and/or circulation). It aims to see which medicine works better and is safer while you are connected to the ECMO circuit.
Sydney, New South WalesAges 18 years+ - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT02851758Recruiting
Autologous mitochondria treatment for critically ill heart children on ECMO
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Boston, MassachusettsAges Up to 17 years - NCT05303363Recruiting
Checking brain blood flow during a breathing heart-lung machine
This study monitors how much blood is reaching the brain in adults who need a specific type of life-support called VV-ECMO. The goal is to better understand brain blood flow and how monitoring may help manage care during ECMO.
Amsterdam-ZuidoostAges 18–100 - NCT06275555Recruiting
Bivalirudin for blood thinning in ECMO patients
This trial tests if bivalirudin is a safe and effective blood thinner for people on ECMO, a machine that helps your heart and lungs. You may be eligible if you need this therapy and have no past reactions to similar medicines.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT04273607RecruitingPhase 2/Phase 3
Test an ECMO approach without blood thinners for lung failure
This trial studies whether people on a breathing machine called VV-ECMO can be managed without routine blood thinners, to reduce bleeding risk. It is meant for adults with severe lung failure (ARDS) and checks that it is safe for you to avoid anticoagulation.
Toronto, OntarioAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT05698628Recruiting
Timing strategies to protect legs during peripheral ECMO
This trial studies whether an “early” or more “conservative” approach to improving blood flow to the leg can prevent limb damage during a type of heart-lung machine called peripheral VA-ECMO. It may help reduce the risk of poor leg blood flow (ischemia) in people with severe heart failure-related shock.
SeoulAges 19 years+ - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06750536Recruiting
Safety study of a new lung support device for small children
This trial is testing a new device (MiniLung Petite Kit) for babies and young children with severe lung or heart failure. The device helps oxygenate the blood and remove carbon dioxide, giving the lungs and heart a chance to rest and heal.
Bonn, North Rhine-WestphaliaAges Up to 8 months - NCT06766006Recruiting
Heart-lung machine left ventricle unloading study
This study looks at how to best relieve pressure on the heart while a heart-lung machine is helping to pump blood. It includes anyone who needs this support.
MaastrichtAges 1 day–80 years - NCT06792643RecruitingPhase 2
Cangrelor for heart attack patients on heart-lung support
This trial tests whether adding a fast-acting anti-clotting drug (cangrelor) helps people having a massive heart attack who need a heart-lung machine (VA-ECMO). The goal is to see if it reduces clotting risks without causing dangerous bleeding.
Milan, ItalyAges 18 years+ - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT07127718RecruitingPhase 2
Preventing complications from leptospirosis
This trial tests ways to prevent early and late complications of leptospirosis, a bacterial infection. It aims to offer treatments that may reduce the risk of serious problems like kidney failure or breathing difficulties.
Manila, National Capital RegionAges 18–60 - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT06872021Recruiting
Early balloon pump use after heart-lung bypass
This trial tests if using a heart pump (IABP) early after starting a life support machine (VA-ECMO) helps people recover from cardiogenic shock. It looks for patients whose heart is not pumping well despite support.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for extracorporeal membrane oxygenation complication?
- Yes. Clin2 currently lists 24 recruiting extracorporeal membrane oxygenation complication studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extracorporeal membrane oxygenation complication trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extracorporeal membrane oxygenation complication trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.