MELK inhibitor safety study for advanced breast cancer
Part of Cancer, Skin clinical trials.
This Phase 1 study tests how safe a drug called an MELK inhibitor is in people with advanced breast cancer that has spread or cannot be removed with surgery. If you qualify, the study is focused on side effects and includes a special group for triple-negative breast cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a woman, age 18 or older, and able to sign consent
- You must have breast cancer that is advanced or metastatic (has spread)
- Your cancer must be returned after prior treatment or there is no standard treatment, and it cannot be removed with surgery
- Your health status must be good enough for treatment (ECOG performance 0–1) and you must have at least 3 months to live
- Recent chemo and/or radiation side effects must be mostly gone (to grade 1 or lower, except mild/controlled nerve symptoms)
- You must be able to use reliable birth control during the study and for 3 months after the last dose (or you cannot get pregnant)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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