Surgery vs focused radiation for early lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This trial compares two ways to treat early-stage lung cancer: surgery or a precise type of radiation called stereotactic radiotherapy. It aims to find out which approach works best for people whose cancer is small and has not spread.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older, and you can understand and sign consent
- Your lung cancer is stage I (early stage) and is suspicious on scans—biopsy confirmation is required later
- Your tumor is 5 cm or smaller on CT (scan measurements)
- Your breathing test results are strong enough for treatment (FEV1 and DLCO each at least 40% of predicted)
- You must be well enough to do the recommended procedure (Karnofsky score 70 or higher)
- Your cancer must not have spread to lymph nodes or distant sites on required tests (PET/CT plus node/lesion biopsy if needed)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two treatments—removing only part of the lung (sublobar resection) versus a focused radiation approach (stereotactic ablative radiotherapy)—for early-stage non-small cell lung cancer. It aims to see which option works better with fewer problems for the right patients.
This trial studies whether giving different cancer medicines before (and sometimes after) surgery improves outcomes for people with early-stage, operable lung cancer that has certain tumor markers. It may help by trying to shrink or control the cancer early and lower the chance it comes back.
This study looks at two treatment options for early-stage lung cancer in patients who are considered 'high-risk' because of poor lung function or other health issues. The goal is to compare outcomes from a surgical approach (removing just the tumor and a small rim of tissue) versus a precise, shorter course of radiation therapy.
This trial studies a precise, high-dose radiation technique (SBRT) to treat tumors in the lungs. It may help control cancer in people who either have early-stage lung cancer that is not fully operable or have limited lung metastases from other cancers.
This trial studies how detailed tests (“multi-omics” modeling) can improve how doctors plan and deliver stereotactic body radiotherapy (SBRT) for early-stage non-small cell lung cancer. It may help make treatment planning more precise for cancers in stages I–II.
This trial tests adding targeted radiation before standard immunotherapy and chemotherapy for people with stage 2-3 non-small cell lung cancer that can be surgically removed. The goal is to see if the radiation helps shrink the tumor more before surgery.
Hear when a new Lung Neoplasm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.