Tests gluten-free diet for people with back pain and gut symptoms
Part of Digestive system, Hormones & metabolism clinical trials.
This study looks at whether a gluten-free diet can improve symptoms in people who fit certain back-pain patterns and certain wheat/gluten-related gut conditions. It also uses food testing (including wheat challenges) to sort out which people truly respond to wheat.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have inflammatory back pain symptoms: morning stiffness over 30 minutes, back pain better with exercise than rest, pain waking you in the late night, and/or alternating buttock pain
- You must also meet the study’s gut condition pattern, such as confirmed celiac disease by blood tests and intestine biopsy changes, or another specific gluten/wheat-related syndrome
- If you’re in the gluten/wheat-sensitive group, your blood tests for celiac should be negative and wheat allergy testing (IgE/skin tests) should be negative
- You must be willing to follow an elimination diet first and then take part in controlled food challenges (including wheat, and sometimes other foods) if you qualify
- You must not have other known stomach/bowel diseases or other diagnosed arthritis/rheumatic conditions that would explain symptoms
- You should not have major nerve disease or a major uncontrolled mental health condition, and you must be physically able to take part in activities
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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