Study brain and voice genetics in people with voice movement disorders
Treatments studied
Part of Brain & nervous system, Ear, nose & throat, Lungs & breathing clinical trials.
This study looks at how genetics and brain patterns are connected to laryngeal dystonia and voice tremor, including people with certain types of voice disorders. You may be asked to do imaging and voice-related assessments to help researchers understand what’s causing these symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Have a diagnosis of laryngeal dystonia (voice muscle spasms) or voice tremor, or be an eligible family member without symptoms
- If you are a patient: your symptoms must match adductor or abductor laryngeal dystonia, and/or essential or dystonic voice tremor, or muscle tension dysphonia
- If you are an unaffected relative: you must be related to someone with familial laryngeal dystonia, or the relative’s onset must be early (age 35 or younger) or typical (age 40 or older)
- Be able to understand and give consent; also be mentally able to complete study steps
- Speak English as your native language and be right-handed
- Be able to do brain/voice imaging (avoid removable metal/ferromagnetic objects you can’t remove; no tattoos that block imaging)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how the brain and voice system work in people with laryngeal dystonia or voice tremor, and compares them with healthy volunteers. The goal is to better describe different “types” (phenotypes) so future care can be more targeted.
This early study uses brain and voice-related testing to better understand what is happening in the brain in people with laryngeal dystonia or voice tremor. The results may help scientists learn more about these conditions and how they differ from healthy voices.
This study tests how a brain–computer interface reads brain signals to understand and possibly support people with a specific voice condition called adductor laryngeal dystonia. It also compares results with healthy people to help researchers see how brain activity differs during voice tasks.
This study tests whether a noninvasive brain stimulation treatment (referred to as neuromodulation, such as rTMS) can improve symptoms of laryngeal dystonia. It’s meant to see if stimulating certain brain areas can reduce how severely your voice/throat problem affects you.
This trial studies deep brain stimulation (a surgically placed device that sends electrical signals) to reduce voice tremor or laryngeal dystonia. You may be considered if your symptoms are persistent despite medication and you can complete the study tasks and pre-surgery testing.
This study tests whether a gentle brain stimulation technique called tDCS can help improve voice control in people with laryngeal dystonia. It aims to find a new way to reduce muscle spasms in the voice box.
Hear when a new Laryngeal Dystonia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.