Simvastatin for Graves eye disease in mild-to-moderate cases
Treatments studied
Part of Eyes & vision, Genetic & congenital, Hormones & metabolism, Immune system & allergy clinical trials.
This trial tests whether simvastatin (a cholesterol medicine) can improve eye symptoms from Graves’ eye disease. It is aimed at people with active mild-to-moderate disease and will also check safety with blood tests, heart/skin tolerance, and stomach health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 70
- You have active mild-to-moderate Graves eye disease (not the severe type)
- Your thyroid levels are normal after stopping anti-thyroid medicine, or after a treatment like radioiodine or surgery (and you must be on correct thyroid replacement during the study if needed)
- You are not pregnant and not breastfeeding
- You have not taken simvastatin or other statins in the last 3 months
- You do not have major safety problems like serious heart failure, significant kidney or liver test abnormalities, statin allergy, active stomach ulcer, or certain blood-thinning conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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