Clinical trials
Graves Ophthalmopathy clinical trials
Below are recruiting graves ophthalmopathy clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06588764Recruiting
Modified eye surgery for moderate to severe Graves' eye disease
This trial tests a modified orbital decompression surgery to treat moderate-to-severe swelling and bulging of the eyes caused by Graves' disease. It aims to improve eye function and appearance for people whose thyroid condition has been stable for at least 6 months.
Guangzhou, GuangdongAges 18–80 - NCT03131726RecruitingPhase 3
Simvastatin for Graves eye disease in mild-to-moderate cases
This trial tests whether simvastatin (a cholesterol medicine) can improve eye symptoms from Graves’ eye disease. It is aimed at people with active mild-to-moderate disease and will also check safety with blood tests, heart/skin tolerance, and stomach health.
MalmöAges 18–70 - NCT06693856Enrolling by invitation
Steroid pulse therapy for active Graves' eye disease
This study tests whether high-dose steroid pulses (given through a vein) can help people with moderate to severe Graves' eye disease that is still active. It is for people who have not yet been treated with steroids and whose eye problems began within the past year.
Shanghai, Shanghai MunicipalityAges 25–70 - NCT07716397Recruiting
MRI study for thyroid eye disease diagnosis and care
This study uses MRI scans of the eye area to better understand and classify thyroid eye disease (TED). It aims to help doctors predict outcomes and personalize treatment. You may be eligible if you have stable TED or are a healthy volunteer.
Shanghai, Huangpu DistrictAges 18–75 - NCT05678374Recruiting
Looking for immune signs linked to mental fatigue in Graves’ disease
This study looks at blood “immune” markers to understand why some people with Graves’ disease develop mental fatigue (feeling slowed down in thinking). It may help doctors better recognize and explain mental fatigue in Graves’ disease.
GothenburgAges 18–72 - NCT07480720Recruiting
Thyroid autoimmunity and eye changes in Graves disease
This study looks at how inflammation and thyroid autoimmunity in Graves disease may cause changes in the retina at the back of the eye. It uses a special eye scan (OCT) to measure those changes and compares results between people with Graves disease and healthy volunteers.
Elâzığ, ElaziğAges 18 years+ - NCT06112340RecruitingPhase 2/Phase 3
Extension study of linsitinib for thyroid eye disease
This trial tests two doses of an oral medication (linsitinib) for people with active, moderate-to-severe thyroid eye disease who were in a previous study and didn't improve enough or had their bulging come back. It aims to see if continuing treatment can help with eye bulging and other symptoms.
Miami, FloridaAges 18 years+ - NCT06275373Recruiting
Teprotumumab for thyroid eye disease study
This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).
Bethesda, MarylandAges 18 years+ - NCT07547930RecruitingPhase 2
Tofacitinib for Steroid-Resistant Thyroid Eye Disease
This study tests whether tofacitinib, a new type of immune-modulating medication, can help people with moderate-to-severe thyroid eye disease (Graves' orbitopathy) whose eyes haven't improved with standard steroid treatments. The goal is to reduce eye swelling, bulging, and inflammation that affects daily life.
Xiamen, FujianAges 18–75 - NCT03708627RecruitingEarly Phase 1
Bimatoprost for eye swelling in Graves’ orbitopathy
This early study tests whether bimatoprost (eye drops) can reduce signs of Graves’ orbitopathy, a condition that can cause bulging eyes. It may help improve eye symptoms for people whose Graves-related eye problems are present.
Seattle, WashingtonAges 18 years+ - NCT05126147RecruitingPhase 4
Hydroxychloroquine for mild Graves’ eye swelling
This trial studies whether hydroxychloroquine can improve mild Graves’ orbitopathy (swelling and discomfort around the eyes). It’s meant for people with mild symptoms and who haven’t recently used certain eye or immune treatments.
HsinchuAges 18–75 - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT07400757Recruiting
Statin and vitamin D for active thyroid eye disease
This trial tests whether a statin (a cholesterol-lowering medicine) combined with vitamin D can improve active thyroid eye disease. It may help if you have both eye inflammation and high cholesterol.
Taipei, TaiwanAges 20 years+ - NCT06392906RecruitingPhase 3
Radiation for Graves' Eye Disease: 1 vs 2 Weeks
This trial tests if a shorter course of radiation (1 week) works as well as a standard longer course (2 weeks) for treating active thyroid eye disease that did not improve enough with steroid medicine. It may be an option if you still have eye symptoms after steroid treatment.
Bangkok NoiAges 18–70
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Common questions
- Are there clinical trials for graves ophthalmopathy?
- Yes. Clin2 currently lists 14 recruiting graves ophthalmopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a graves ophthalmopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a graves ophthalmopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.