Clarithromycin versus azithromycin for lung MAC infection
Treatments studied
Part of Infections, Lungs & breathing clinical trials.
This Phase 3 trial compares two antibiotics—clarithromycin and azithromycin—to treat lung infection caused by Mycobacterium avium complex (MAC). It may help by showing which antibiotic works better and is safer for people who need MAC treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older
- Your MAC test sample is positive and meets doctor criteria for MAC lung infection (symptoms/imaging plus lab results)
- CT scan, scope (fibroscopy/bronchoscopy), and culture tests do not suggest another lung diagnosis
- You have no allergy or bad reaction to study antibiotics (clarithromycin or azithromycin) and related study medicines
- Your MAC bacteria are not resistant to “macrolide” antibiotics (a test must be done before enrollment)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an inhaled antibiotic (amikacin liposome) for people with a lung infection caused by a germ called Mycobacterium xenopi. The goal is to see if this treatment can help fight the infection with fewer side effects.
This trial tests whether a shorter course of antibiotics works for people with a specific type of lung infection caused by Mycobacterium avium complex (MAC). It aims to find a treatment that is just as effective but easier to complete.
This trial tests whether the drug Contezolid can quickly kill the bacteria that cause MAC lung disease, a type of lung infection. It is for people who have not been treated for this infection in the last 3 months.
This trial studies how much medicine is needed (based on lab results) to treat MAC lung disease, an infection in the lungs. If you already have MAC and are receiving the recommended core antibiotics, your care may help researchers link treatment details to lab measurements.
This trial tests whether inhaled hypertonic saline can improve symptoms and lung health in people with a specific lung infection called MAC. It targets adults with confirmed MAC infection and bronchiectasis who are not already on certain MAC medications.
This study follows people with a newly diagnosed MAC lung infection (a specific type of mycobacterial disease) and tests how they do on the standard three-drug treatment plan. It may help researchers better understand outcomes and safety for this condition.
Hear when a new Lung Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.