Hypertonic saline to treat MAC lung infection
Treatments studied
Part of Infections clinical trials.
This trial tests whether inhaled hypertonic saline can improve symptoms and lung health in people with a specific lung infection called MAC. It targets adults with confirmed MAC infection and bronchiectasis who are not already on certain MAC medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older
- Have MAC confirmed by sputum (phlegm) tests: at least 2 positive MAC cultures in the last 12 months
- Have at least one AFB-positive sputum sample within 12 weeks before starting
- Have bronchiectasis seen on a chest CT scan (or bronchiectasis-type findings)
- Be able to consent and follow the study plan
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether inhaling hypertonic (very salty) saline helps treat nodular-bronchiectatic lung disease caused by Mycobacterium avium complex (MAC). It may help reduce ongoing infection and symptoms if you have the right type of MAC lung pattern and have not recently started the usual MAC treatments.
This trial tests whether breathing salt water vapor through a home nebulizer machine helps people with a specific type of lung infection (nontuberculous mycobacteria). The goal is to see if this simple treatment can improve breathing and reduce symptoms.
This study will look at people with a lung infection called nontuberculous mycobacterial lung disease to find out more about how their immune system reacts. If you have this condition, your medical history and possibly a lung sample can help researchers understand why some people get sicker than others.
This trial tests whether a shorter course of antibiotics works for people with a specific type of lung infection caused by Mycobacterium avium complex (MAC). It aims to find a treatment that is just as effective but easier to complete.
This trial studies how much medicine is needed (based on lab results) to treat MAC lung disease, an infection in the lungs. If you already have MAC and are receiving the recommended core antibiotics, your care may help researchers link treatment details to lab measurements.
This Phase 3 trial compares two antibiotics—clarithromycin and azithromycin—to treat lung infection caused by Mycobacterium avium complex (MAC). It may help by showing which antibiotic works better and is safer for people who need MAC treatment.
Hear when a new Nontuberculous Mycobacterial Lung Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.