Proton pump medicine effect on esophagus in eosinophilia
Part of Blood & lymphatic, Digestive system, Immune system & allergy clinical trials.
This pilot study looks at how proton pump inhibitor medicines (acid reducers) change the flexibility of the esophagus in people who have eosinophilia on esophagus biopsy. It may help doctors understand whether acid control could improve esophagus function in this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have eosinophils on esophagus biopsy: more than 15 eosinophils per high-power microscope view
- Those biopsy results come from at least 2 of these areas: upper, middle, and lower esophagus
- Other known causes of esophageal eosinophilia (like infections, celiac disease, Crohn’s, or medication reactions) have been ruled out
- Your age is between 18 and 65 years
- You can safely have an esophagus biopsy (no bleeding-risk issues or esophageal varices)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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