Targeted radiation for spinal metastases causing significant pain
Part of Cancer, Kidney & urinary, Lungs & breathing, Skin clinical trials.
This trial tests a focused form of radiation (stereotactic body radiation) to treat cancer spread to the spine, especially when it causes substantial pain. It may help shrink or control the spinal spots while limiting damage to surrounding tissues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your overall health status is very good (WHO score 0–2)
- The original tumor diagnosis is confirmed by biopsy/pathology, and the spinal spots are confirmed by scans or biopsy
- Your spinal metastases are limited to 3 straight vertebral levels in a row
- You have significant back pain (pain score 5 or higher), and your pain medicines are recorded
- You can get an enhanced MRI of the involved spine within 2 weeks before radiation
- Your blood and organ tests are within required ranges (blood counts, liver, and kidney) and you can sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a type of focused radiation given in smaller parts to treat bone metastases from breast cancer. It may help shrink tumors and improve control of pain or growth when standard treatments haven’t worked or surgery isn’t possible.
This trial tests whether adding precise radiation to a procedure that uses heat and bone cement can better relieve pain from cancer that has spread to the spine. It is for people with one or two painful spots in the middle to lower back.
This trial tests a stronger, carefully measured form of radiation aimed at a small number of spots where cancer has spread to the spine. It may help control pain and tumor growth while protecting the spinal cord.
This trial tests whether lower radiation doses work well for treating cancer that has spread to the spine. If you have a few spine tumors that are stable or causing symptoms, this study might help doctors find safer, faster treatment options.
This Phase 2 study tests a precise radiation treatment (spine SBRT, also called radiosurgery) to reduce pain from cancer that has spread to the spine. It focuses on people with stable spine structure and low pain at the start, to see how well the treatment works and stays safe.
This trial compares two types of radiation therapy—standard palliative radiation and a more targeted high-dose treatment (SBRT)—to see which better relieves pain from bone metastases that have spread outside the spine. It is for people with solid tumors who have a painful bone spot and are expected to live at least 6 months.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.