Cartilage repair for knee damage in teens
Part of Bones, joints & muscles clinical trials.
This trial tests two ways to repair damaged knee cartilage in young people: one uses your own cartilage cells grown in a lab (MACI), and the other is a standard procedure called microfracture. The goal is to see which works better to reduce pain and improve knee function, and to help you get back to normal activities.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 10 and 17 years old.
- You have knee pain from damaged cartilage or a bone-cartilage injury that hasn't healed.
- The damaged area is at least 1.5 square centimeters (about the size of a coin).
- The damaged area has not been previously repaired with surgery.
- You do not have other joint diseases (like rheumatoid arthritis), a history of knee infection, or active cancer.
- You are not pregnant or breastfeeding (if female).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a treatment called MACI for people with damaged cartilage in their ankle. It uses your own cells to grow new cartilage, which may help reduce pain and improve how you can use your ankle.
This study compares two surgical techniques to repair large cartilage or bone defects in the knee, which can cause pain and limit movement. If you have a significant knee injury that hasn't improved with other treatments, you may be able to join and help find which method works best.
This study tests a new implant made from your own cells to repair damaged knee cartilage. It aims to reduce pain and improve knee function by replacing the damaged area with a living implant.
This Phase 2 study tests CartiLife® to help repair a specific type of damaged knee cartilage. You may be considered if you have a moderate-sized cartilage defect in the knee and enough pain and function limits to need treatment.
This trial tests a cartilage-repair procedure called ACI for people whose knee cartilage injury has not improved after at least 6 months of prior treatment. If you qualify, it may help your cartilage heal and reduce symptoms.
This study follows adults who are already scheduled for ACI surgery (a procedure that uses your own cartilage cells to repair knee injuries). It measures how well the knee works after surgery.
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