Cartilage repair treatment test for knee joint damage
Part of Bones, joints & muscles clinical trials.
This Phase 2 study tests CartiLife® to help repair a specific type of damaged knee cartilage. You may be considered if you have a moderate-sized cartilage defect in the knee and enough pain and function limits to need treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older and can sign consent
- Your knee has a cartilage injury area between 2 and 10 square centimeters, and the defect is not too large by volume
- The cartilage damage is a Grade III or IV type (not mild cartilage wear)
- Your knee alignment is close to normal (within 5 degrees), and your knee ligaments are stable enough for normal movement
- You still have enough of your meniscus (more than half is intact, even if partially damaged)
- Your starting knee pain score is under 60 (KOOS pain), and you can follow the rehab and follow-up plan
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a cartilage-repair procedure called ACI for people whose knee cartilage injury has not improved after at least 6 months of prior treatment. If you qualify, it may help your cartilage heal and reduce symptoms.
This trial compares two surgical approaches to repair large areas of damaged cartilage and the bone under it in the knee. It’s for people who still have symptoms despite non-surgical treatment, and it may help improve recovery and knee function.
This trial tests a treatment called MACI for people with damaged cartilage in their ankle. It uses your own cells to grow new cartilage, which may help reduce pain and improve how you can use your ankle.
This study follows adults who are already scheduled for ACI surgery (a procedure that uses your own cartilage cells to repair knee injuries). It measures how well the knee works after surgery.
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This trial tests if a cell-based treatment called CARTISTEM can repair knee cartilage better than surgery alone. It involves people with knee osteoarthritis and a cartilage defect, with moderate pain and limited function.
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