Testing an oral drug for GIST or other solid tumors
Part of Cancer, Digestive system clinical trials.
This Phase 1 trial tests HQP1351, a new oral cancer drug, in people with advanced GIST or other solid tumors that have not responded to prior treatment. It’s mainly designed to check safety and how the drug works in the body, which may lead to better options for tumors that have progressed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 12 or older, and you’re either male or a woman who isn’t pregnant or breastfeeding.
- You have advanced or metastatic GIST or another solid tumor confirmed by biopsy or similar testing.
- Your tumor is resistant to imatinib (a standard GIST medicine) or you’ve had treatment that stopped working after at least 6 months (and then the tumor grew again).
- Your overall health score is ECOG 0–2, and you’re expected to live at least 3 months.
- Your blood counts and organ functions (kidneys and liver) are strong enough for study treatment.
- Your heart and heart rhythm tests are within safe limits (including blood troponin level, heart pumping strength, and QT interval).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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