Testing a lower INR goal to reduce bleeding in mechanical valves
Treatments studied
Part of Heart & circulation clinical trials.
This Phase 3 study tests whether aiming for a lower blood-thinning test result (INR) can reduce bleeding risk in people with a specific type of mechanical heart valve. The trial checks if this lower INR goal is safer while still protecting against dangerous clots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older
- You have a bileaflet mechanical heart valve in your aortic valve area placed at least 3 months ago
- You (or your legal decision-maker) can sign consent to join the study
- You do not have any additional mechanical heart valve implanted in any location
- Your target INR plan will not go below 2.0
- You are not pregnant and do not expect to become pregnant during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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