Clin2
NCT03643367Possibly a fitNot yet recruiting

Sevoflurane sedation for septic shock in the intensive care unit

Shock, Septic

Treatments studied

Part of Infections clinical trials.

This study tests a special type of sedative (sevoflurane, given as a gas) to see if it helps people with septic shock who are on breathing machines. It might improve recovery compared to standard care.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
153 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old.
  • You are in the intensive care unit (ICU) with septic shock (a severe infection causing very low blood pressure) and need medicine to keep your blood pressure up.
  • You are sedated (asleep) and on a breathing machine (ventilator).
  • You have been on blood pressure medicine for less than 12 hours.
  • If you are a woman who can have children, you must have a negative pregnancy test.
  • You must not have had surgery or anesthesia in the last 7 days, and you must not have certain other serious health conditions (like heart failure, severe kidney disease, or a current cancer treatment).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07000526Recruiting· Phase 4
Inhaled sedation for critically ill patients on breathing machines

This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.

Orihuela, Alicante
NCT07457593AVAILABLE
Inhaled isoflurane for hard-to-sedate ICU patients

This trial provides access to an inhaled sedative (isoflurane) for ICU patients who are on a breathing tube and cannot be safely sedated with standard IV medicines. It aims to help patients who are agitated, need high doses of sedatives, or have side effects from current sedation.

NCT06014138Recruiting· Phase 2/Phase 3
Volatile sedation study for ARDS patients

This trial is comparing a new type of inhaled sedative (volatile sedation) to usual IV sedatives for people with ARDS who are on a ventilator in the ICU. It aims to see if it can help patients breathe better and recover more quickly.

London, London
NCT07099014Not yet recruiting· Phase 3
Inhaled isoflurane for sedation during ECMO for heart shock

This study tests an inhaled sedative called isoflurane to keep patients calm while on a breathing machine and ECMO for severe heart failure. It may be an alternative to standard IV sedatives.

NCT05680545Not yet recruiting
How sevoflurane anesthesia works in the body during ECMO

This study looks at how the body processes the inhaled anesthetic sevoflurane while a person is on a heart-lung support machine called ECMO. It aims to make sedation dosing safer and more effective for people on this support.

NCT06731088Enrolling by invitation· Phase 4
Sedation with remazolam and remifentanil for sepsis patients

This study tests a combination of two sedative drugs (remazolam besylate and remifentanil) for calming patients with sepsis who are on a ventilator in the ICU. The goal is to see if this approach improves recovery compared to standard care.

Ningbo, Zhejiang

Hear when a new Shock, Septic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.