Inhaled isoflurane for sedation on ECMO in cardiogenic shock
Part of Heart & circulation clinical trials.
This trial tests if an inhaled sedative called isoflurane can be used safely and effectively in people who are on a heart-lung machine (ECMO) for severe heart failure (cardiogenic shock) and also need a breathing tube. It compares isoflurane to standard sedatives (propofol and midazolam).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe heart failure that requires a heart-lung machine (ECMO), and it was started less than 24 hours ago.
- You have a breathing tube and are receiving standard sedatives (propofol or midazolam).
- You have been on the breathing machine for less than 48 hours.
- You are between 18 and 75 years old.
- You do not have certain heart rhythm problems, severe liver disease, or allergies to the study drugs.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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