Sevoflurane sedation monitoring during VV ECMO
Part of Lungs & breathing clinical trials.
This study measures how well the anesthesia medicine sevoflurane moves through the body in people receiving VV ECMO (a heart-lung machine). It may help doctors better manage sedation and dosing during long ECMO support.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (18+) and expected to be on VV ECMO for more than 24 hours.
- You are receiving sedation that uses sevoflurane.
- You (or your legal representative) can give informed consent to join the study.
- You are not currently pregnant.
- Your recent lab and treatments should fit the limits: bilirubin is not very high, and you are not in certain intense blood-filtering treatments.
- You are not likely to die or have life support withdrawn within the next 48 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if an inhaled sedative called isoflurane can be used safely and effectively in people who are on a heart-lung machine (ECMO) for severe heart failure (cardiogenic shock) and also need a breathing tube. It compares isoflurane to standard sedatives (propofol and midazolam).
This Phase 2 study tests whether a specific inhaled sedative (sevoflurane) is safe and helpful for people with septic shock who need ICU sedation and a breathing machine. It may improve how patients tolerate intensive care treatment, but eligibility is limited to a short time window after septic shock begins.
This study is testing a sedative medicine (sevoflurane) to help people with a difficult airway breathe more easily during a procedure. It may be an alternative to being awake while a tube is placed in your windpipe.
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
This Phase 3 trial tests whether inhaled sevoflurane (a breathing anesthetic) can help prevent ARDS, a serious lung injury, in high-risk ICU patients who need sedation. It aims to reduce the chance of developing ARDS by using this medication during the early period on a breathing machine.
This study looks at brain activity (EEG) in children while they are under sevoflurane anesthesia. It may help doctors better understand how anesthesia affects the brain in young children.
Hear when a new Respiratory Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.