Inhaled sedation for critically ill patients on breathing machines
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are on a breathing machine (mechanical ventilation) and are expected to need it for more than 48 hours.
- You require deep sedation (target score between -3 and -5 on the RASS scale).
- You are not allergic to isoflurane or propofol.
- You have no significant air leaks from your lungs (less than 30% of your breath volume).
- You have no history of dangerous heart rhythms (ventricular tachycardia or long QT syndrome).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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